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SCO3478 protein (Streptomyces coelicolor) - STRING interaction network
"SCO3478" - SCE65.14c, probable dehydrogenase, len: 344 aa in Streptomyces coelicolor
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Known Interactions
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Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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Gene Fusion
SCO3478SCE65.14c, probable dehydrogenase, len- 344 aa; similar to TR-O50095 (EMBL-AP000006) Pyrococcus horikoshii 307aa long hypothetical phosphoglycerate dehydrogenase PH1387, 307 aa; fasta scores- opt- 687 z-score- 777.1 E()- 0; 40.5% identity in 291 aa overlap and to SW-SERA_METTH (EMBL-AE000870;) Methanobacterium thermoautotrophicum D-3-phosphoglycerate dehydrogenase (EC SerA, 525 aa; fasta scores- opt- 664 z-score- 748.1 E()- 0; 39.0% identity in 282 aa overlap. Contains Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenases and match to Prosite [...] (344 aa)    
Predicted Functional Partners:
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily (363 aa)
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily (253 aa)
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (511 aa)
SCE65.13c, possible dehydrogenase, len- 344 aa; similar to TR-CAB50292 (EMBL-AJ248287) Pyrococcus abyssi threonine 3-dehydrogenase (EC 348 aa; fasta scores- opt- 567 z-score- 616.8 E()- 5.6e-27; 33.8% identity in 328 aa overlap and to SW-TDH_BACSU (EMBL-Z99112) threonine 3-dehydrogenase (EC 1.1.103) Tdh, 347 aa; fasta scores- opt- 544 z-score- 592.1 E()- 1.3e-25; 31.4% identity in 331 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases (344 aa)
Putative short-chain dehydrogenase; SCE65.12c, probable dehydrogenase, len- 251 aa; similar to SW-KDUD_BACSU (EMBL-L47838) Bacillus subtilis 2-deoxy-D-gluconate 3-dehydrogenase (EC KduD, 254 aa; fasta scores- opt- 833 z-score- 937.8 E()- 0; 52.0% identity in 248 aa overlap and to Streptomyces coelicolor SCI30A.02, 253 aa; fasta scores- opt- 605 z-score- 622.2 E()- 2.7e-29; 44.1% identity in 245 aa overlap. Contains Pfam matches to entry PF00106 adh_short, short chain dehydrogenase and to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus and match to [...] (251 aa)
D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family (529 aa)
Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family (485 aa)
Phosphate acetyltransferase; Involved in acetate metabolism; In the N-terminal section; belongs to the CobB/CobQ family (697 aa)
SCE65.11c, possible isomerase, len- 377 aa; similar to SW-ATB_RHOOP (EMBL-X99622) Rhodococcus opacus muconate cycloisomerase I (EC CatB, 373 aa; fasta scores- opt- 390 z-score- 443.3 E()- 2.6e-17; 31.1% identity in 357 aa overlap. Contains Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme family PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2 (377 aa)
Phenylalanine--tRNA ligase beta subunit; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily (840 aa)
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor, Streptomyces coelicolor A3(2)
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