node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO1944 | SCO3005 | gene:17759541 | gene:17760617 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.999 |
SCO1944 | SCO3880 | gene:17759541 | gene:17761507 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | 0.945 |
SCO1944 | SCO3881 | gene:17759541 | gene:17761508 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Putative ribonuclease P component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.690 |
SCO1944 | SCO3883 | gene:17759541 | gene:17761510 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). | 0.992 |
SCO1944 | SCO4646 | gene:17759541 | gene:17762295 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
SCO1944 | SCO4722 | gene:17759541 | gene:17762371 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
SCO1944 | SCO5586 | gene:17759541 | gene:17763244 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.990 |
SCO1944 | SCO6160 | gene:17759541 | gene:17763819 | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | Putative SecDF protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.999 |
SCO3005 | SCO1944 | gene:17760617 | gene:17759541 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | 0.999 |
SCO3005 | SCO3880 | gene:17760617 | gene:17761507 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | 0.722 |
SCO3005 | SCO3883 | gene:17760617 | gene:17761510 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). | 0.987 |
SCO3005 | SCO4646 | gene:17760617 | gene:17762295 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
SCO3005 | SCO4722 | gene:17760617 | gene:17762371 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.999 |
SCO3005 | SCO5586 | gene:17760617 | gene:17763244 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.989 |
SCO3005 | SCO6160 | gene:17760617 | gene:17763819 | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | Putative SecDF protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.997 |
SCO3880 | SCO1944 | gene:17761507 | gene:17759541 | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | 0.945 |
SCO3880 | SCO3005 | gene:17761507 | gene:17760617 | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.722 |
SCO3880 | SCO3881 | gene:17761507 | gene:17761508 | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | Putative ribonuclease P component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.998 |
SCO3880 | SCO3882 | gene:17761507 | gene:17761509 | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.937 |
SCO3880 | SCO3883 | gene:17761507 | gene:17761510 | StH24.02, rpmH, probable 50S ribosomal protein L34, len: 45 aa; previously sequenced as SW:RL34_STRCO (EMBL:M82836), rpmH. Similar to many e.g. SW:RL34_STRBI (EMBL:M83112), rpmH, Streptomyces bikiniensis 50S ribosomal protein L34 (45 aa), fasta scores; opt: 266 z-score: 448.4 E(): 1.2e-17, 91.1% identity in 45 aa overlap. Contains Pfam match to entry PF00468 Ribosomal_L34, Ribosomal protein L34, score 75.20, E-value 1.2e-20 and PS00784 Ribosomal protein L34 signature; Belongs to the bacterial ribosomal protein bL34 family. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). | 0.976 |