node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO1481 | SCO1488 | gene:17759067 | gene:17759074 | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.996 |
SCO1481 | SCO4041 | gene:17759067 | gene:17761672 | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.971 |
SCO1481 | SCO4152 | gene:17759067 | gene:17761796 | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | SCD84.19, possible secreted 5'-nucleotidase, len: 612 aa; similar to SW:5NTD_DISOM (EMBL:X62278) Discopyge ommata 5'-nucleotidase precursor (EC 3.1.3.5) (ecto-nucleotidase), 577 aa; fasta scores: opt: 322 z-score: 332.6 E(): 4.6e-11; 24.6% identity in 574 aa overlap. Contains Pfam match to entry PF01009 5_nucleotidase, 5'-nucleotidase and possible N-terminal region signal peptide sequence; Belongs to the 5'-nucleotidase family. | 0.903 |
SCO1481 | SCO4785 | gene:17759067 | gene:17762434 | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.675 |
SCO1481 | SCO4909 | gene:17759067 | gene:17762558 | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | SCK13.01c, possible ATP-binding protein, len: 258 aa. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). | 0.922 |
SCO1481 | SCO5626 | gene:17759067 | gene:17763284 | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.955 |
SCO1488 | SCO1481 | gene:17759074 | gene:17759067 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | SC9C5.05c, pyrF, orotidine 5'-phosphate decarboxylase, len: 278 aa; similar to SW:DCOP_MYCTU (EMBL:Z80108) Mycobacterium tuberculosis orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) PyrF or UraA, 274 aa; fasta scores: opt: 800 z-score: 874.6 E(): 0; 51.1% identity in 282 aa overlap. Contains Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylases and match to Prosite entry PS00156 Orotidine 5'-phosphate decarboxylase active site; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.996 |
SCO1488 | SCO1971 | gene:17759074 | gene:17759568 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. | 0.906 |
SCO1488 | SCO4041 | gene:17759074 | gene:17761672 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.954 |
SCO1488 | SCO4152 | gene:17759074 | gene:17761796 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | SCD84.19, possible secreted 5'-nucleotidase, len: 612 aa; similar to SW:5NTD_DISOM (EMBL:X62278) Discopyge ommata 5'-nucleotidase precursor (EC 3.1.3.5) (ecto-nucleotidase), 577 aa; fasta scores: opt: 322 z-score: 332.6 E(): 4.6e-11; 24.6% identity in 574 aa overlap. Contains Pfam match to entry PF01009 5_nucleotidase, 5'-nucleotidase and possible N-terminal region signal peptide sequence; Belongs to the 5'-nucleotidase family. | 0.901 |
SCO1488 | SCO4634 | gene:17759074 | gene:17762280 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | SCD82.05c, possible hydrolase, len: 434 aa; similar to SW:ATZC_PSESD (EMBL:AF017572) Pseudomonas sp. N-isopropylammelide isopropyl amidohydrolase (EC 3.5.1.-) AtzC, 403 aa; fasta scores: opt: 292 z-score: 291.5 E(): 8.2e-09; 23.5% identity in 383 aa overlap. | 0.906 |
SCO1488 | SCO4785 | gene:17759074 | gene:17762434 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.658 |
SCO1488 | SCO4890 | gene:17759074 | gene:17762539 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 2SCK8.16, deoA, thymidine phosphorylase, len: 427 aa; similar to SW:TYPH_ECOLI (EMBL:U14003) Escherichia coli thymidine phosphorylase (EC 2.4.2.4) DeoA, 440 aa; fasta scores: opt: 874 z-score: 920.7 E(): 0; 41.7% identity in 436 aa overlap. Contains Pfam match to entry PF00591 Glycos_transf_3, glycosyl transferase family and match to Prosite entry PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. | 0.919 |
SCO1488 | SCO4909 | gene:17759074 | gene:17762558 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | SCK13.01c, possible ATP-binding protein, len: 258 aa. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). | 0.914 |
SCO1488 | SCO4917 | gene:17759074 | gene:17762566 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | Putative purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.900 |
SCO1488 | SCO5626 | gene:17759074 | gene:17763284 | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.944 |
SCO1971 | SCO1488 | gene:17759568 | gene:17759074 | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. | Pyrimidine operon regulatory protein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.906 |
SCO1971 | SCO4041 | gene:17759568 | gene:17761672 | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. | Putative uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.909 |
SCO1971 | SCO4634 | gene:17759568 | gene:17762280 | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. | SCD82.05c, possible hydrolase, len: 434 aa; similar to SW:ATZC_PSESD (EMBL:AF017572) Pseudomonas sp. N-isopropylammelide isopropyl amidohydrolase (EC 3.5.1.-) AtzC, 403 aa; fasta scores: opt: 292 z-score: 291.5 E(): 8.2e-09; 23.5% identity in 383 aa overlap. | 0.900 |
SCO1971 | SCO4890 | gene:17759568 | gene:17762539 | Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. | 2SCK8.16, deoA, thymidine phosphorylase, len: 427 aa; similar to SW:TYPH_ECOLI (EMBL:U14003) Escherichia coli thymidine phosphorylase (EC 2.4.2.4) DeoA, 440 aa; fasta scores: opt: 874 z-score: 920.7 E(): 0; 41.7% identity in 436 aa overlap. Contains Pfam match to entry PF00591 Glycos_transf_3, glycosyl transferase family and match to Prosite entry PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. | 0.923 |