STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4414SC6F11.12, possible integral membrane protein, len: 441 aa; similar to TR:BAB06413 (EMBL:AP001516) Bacillus halodurans transporter BH2694, 418 aa; fasta scores: opt: 795 z-score: 909.8 E(): 0; 31.0% identity in 413 aa overlap. Contains possible hydrophobic membrane spanning regions. (441 aa)    
Predicted Functional Partners:
SCO4415
SC6F11.13, possible integral membrane protein, len: 290 aa. Contains possible hydrophobic membrane spanning regions.
       0.705
SCO4413
SC6F11.11c, probable araC family transcriptional regulatory protein, len: 344 aa; highly similar to TR:Q9S166 (EMBL:AB023785) Streptomyces griseus AdpA, 405 aa; fasta scores: opt: 881 z-score: 1024.1 E(): 0; 46.9% identity in 322 aa overlap and to TR:CAB70646 (EMBL:AL137242) Streptomyces coelicolor putative transcriptional regulator SC8F4.20c, 337 aa; fasta scores: opt: 1237 z-score: 1238.7 E(): 0; 60.3% identity in 325 aa overlap. Contains Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family and a possible helix-turn-helix motif at residues [...]
  
    0.586
SCO0196
Hypothetical protein SCJ12.08; SCJ12.08, unknown, len:134 aa. Shares a low level of similarity with Mycobacterium tuberculosis TR:O53597 (EMBL; AL021426) hypothetical 24.0 KD protein MTV028.10C (224 aa), fasta scores opt: 119 z-score: 159.2 E(): 0.1 32.8% identity in 116 aa overlap.
  
  
 0.463
SCO5925
Hypothetical protein; SC10A5.30c, unknown, len: 83 aa.
  
  
 0.463
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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