node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0401 | SCO3311 | gene:17757984 | gene:17760930 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.990 |
SCO0401 | SCO3317 | gene:17757984 | gene:17760936 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | SCE68.15c, possible uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase, len: 565 aa; similar to many e.g. SW:HEM4_CLOJO (EMBL:D28503), hemD, Clostridium josui porphyrin biosynthesis probable bifunctional protein (504 aa), fasta scores; opt: 519 z-score: 562.5 E(): 5.2e-24, 29.8% identity in 533 aa overlap. The C-terminal half is similar to the monofunctional SW:HEM4_SYNP7 (EMBL:X70966) Synechococcus sp. uroporphyrinogen-III synthase (264 aa) (29.7% identity in 263 aa overlap). May be involved in cysteine biosynthesis and/or porphyrin biosynthesis. Contains Pfam match to [...] | 0.644 |
SCO0401 | SCO3318 | gene:17757984 | gene:17760937 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.844 |
SCO0401 | SCO3319 | gene:17757984 | gene:17760938 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | Putative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.980 |
SCO0401 | SCO4469 | gene:17757984 | gene:17762114 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | SCD65.12, hemL, glutamate-1-semialdehyde 2,1-aminomutase, len: 438 aa; highly similar to SW:GSA_ECOLI (EMBL:X53696) Escherichia coli glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) HemL, 426 aa; fasta scores: opt: 1425 z-score: 1497.5 E(): 0; 52.0% identity in 425 aa overlap. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate and match to Prosite entry PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. | 0.924 |
SCO0401 | SCO4470 | gene:17757984 | gene:17762115 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | SCD65.13, probable phosphoglycerate mutase, len: 233 aa; similar to SW:PMG2_ECOLI (EMBL:M97495) Escherichia coli probable phosphoglycerate mutase 2 (EC 5.4.2.1) GpmB, 215 aa; fasta scores: opt: 182 z-score: 227.1 E(): 3.5e-05; 26.5% identity in 215 aa overlap. Contains Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase family. | 0.812 |
SCO0401 | SCO4473 | gene:17757984 | gene:17762118 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | SCD65.16, possible cytochrome biogenesis related protein, len: 253 aa; similar to SW:CCDA_BACSU (EMBL:X87845) Bacillus subtilis cytochrome C-type biogenesis protein CcdA, 235 aa: fasta scores: opt: 454 z-score: 507.4 E(): 8.5e-21; 33.3% identity in 228 aa overlap. Contains match to Prosite entry PS00086 Cytochrome P450 cysteine heme-iron ligand signature. Also contains possible hydrophobic membrane spanning regions. | 0.539 |
SCO0401 | SCO4475 | gene:17757984 | gene:17762120 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | SCD65.18, possible cytochrome biogenesis related protein, len: 380 aa; similar to SW:CCSA_GUITH (EMBL:X52159) Guillardia theta cytochrome biogenesis protein CcsA, 301 aa; fasta scores: opt: 455 z-score: 519.0 E(): 1.9e-21; 35.6% identity in 253 aa overlap. Contains Pfam match to entry PF01578 CytC_asm, Cytochrome C assembly protein and possible hydrophobic membrane spanning regions. | 0.540 |
SCO0401 | SCO6031 | gene:17757984 | gene:17763690 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.668 |
SCO0401 | SCO7343 | gene:17757984 | gene:17765003 | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.851 |
SCO3311 | SCO0401 | gene:17760930 | gene:17757984 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | 0.990 |
SCO3311 | SCO3317 | gene:17760930 | gene:17760936 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | SCE68.15c, possible uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase, len: 565 aa; similar to many e.g. SW:HEM4_CLOJO (EMBL:D28503), hemD, Clostridium josui porphyrin biosynthesis probable bifunctional protein (504 aa), fasta scores; opt: 519 z-score: 562.5 E(): 5.2e-24, 29.8% identity in 533 aa overlap. The C-terminal half is similar to the monofunctional SW:HEM4_SYNP7 (EMBL:X70966) Synechococcus sp. uroporphyrinogen-III synthase (264 aa) (29.7% identity in 263 aa overlap). May be involved in cysteine biosynthesis and/or porphyrin biosynthesis. Contains Pfam match to [...] | 0.996 |
SCO3311 | SCO3318 | gene:17760930 | gene:17760937 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Putative porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SCO3311 | SCO3319 | gene:17760930 | gene:17760938 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Putative glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.986 |
SCO3311 | SCO4469 | gene:17760930 | gene:17762114 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | SCD65.12, hemL, glutamate-1-semialdehyde 2,1-aminomutase, len: 438 aa; highly similar to SW:GSA_ECOLI (EMBL:X53696) Escherichia coli glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) HemL, 426 aa; fasta scores: opt: 1425 z-score: 1497.5 E(): 0; 52.0% identity in 425 aa overlap. Contains Pfam match to entry PF00202 aminotran_3, Aminotransferases class-III pyridoxal-phosphate and match to Prosite entry PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. | 0.998 |
SCO3311 | SCO4475 | gene:17760930 | gene:17762120 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | SCD65.18, possible cytochrome biogenesis related protein, len: 380 aa; similar to SW:CCSA_GUITH (EMBL:X52159) Guillardia theta cytochrome biogenesis protein CcsA, 301 aa; fasta scores: opt: 455 z-score: 519.0 E(): 1.9e-21; 35.6% identity in 253 aa overlap. Contains Pfam match to entry PF01578 CytC_asm, Cytochrome C assembly protein and possible hydrophobic membrane spanning regions. | 0.475 |
SCO3311 | SCO6031 | gene:17760930 | gene:17763690 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.875 |
SCO3311 | SCO7343 | gene:17760930 | gene:17765003 | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
SCO3317 | SCO0401 | gene:17760936 | gene:17757984 | SCE68.15c, possible uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase, len: 565 aa; similar to many e.g. SW:HEM4_CLOJO (EMBL:D28503), hemD, Clostridium josui porphyrin biosynthesis probable bifunctional protein (504 aa), fasta scores; opt: 519 z-score: 562.5 E(): 5.2e-24, 29.8% identity in 533 aa overlap. The C-terminal half is similar to the monofunctional SW:HEM4_SYNP7 (EMBL:X70966) Synechococcus sp. uroporphyrinogen-III synthase (264 aa) (29.7% identity in 263 aa overlap). May be involved in cysteine biosynthesis and/or porphyrin biosynthesis. Contains Pfam match to [...] | SCF62.27, possible aminotransferase, len: 441 aa. Similar to many including Pseudomonas aeruginosa SW:GSA_PSEAE (EMBL:X82072) glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (glutamate-1-semialdehyde aminotransferase) (427 aa), fasta scores opt: 475 z-score: 540.8 E(): 9.5e-23 34.8% identity in 434 aa overlap and Streptomyces coelicolor TR:CAB39702 (EMBL: AL049485) probable aminotransferase SC6A5.18 (461 aa), fasta scores opt: 464 z-score: 527.9 E(): 4.9e-22 32.4% identity in 407 aa overlap. Contains 2x Pfam matches to entry PF00202 aminotran_3, Aminotransferases class-III pyrido [...] | 0.644 |
SCO3317 | SCO3311 | gene:17760936 | gene:17760930 | SCE68.15c, possible uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase, len: 565 aa; similar to many e.g. SW:HEM4_CLOJO (EMBL:D28503), hemD, Clostridium josui porphyrin biosynthesis probable bifunctional protein (504 aa), fasta scores; opt: 519 z-score: 562.5 E(): 5.2e-24, 29.8% identity in 533 aa overlap. The C-terminal half is similar to the monofunctional SW:HEM4_SYNP7 (EMBL:X70966) Synechococcus sp. uroporphyrinogen-III synthase (264 aa) (29.7% identity in 263 aa overlap). May be involved in cysteine biosynthesis and/or porphyrin biosynthesis. Contains Pfam match to [...] | Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family. | 0.996 |