node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO1232 | SCO2510 | gene:17758815 | gene:17760112 | Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | Conserved hypothetical protein SCC121.13c; Involved in DNA repair and RecF pathway recombination. | 0.628 |
SCO1232 | SCO4752 | gene:17758815 | gene:17762401 | Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.857 |
SCO2510 | SCO1232 | gene:17760112 | gene:17758815 | Conserved hypothetical protein SCC121.13c; Involved in DNA repair and RecF pathway recombination. | Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.628 |
SCO2510 | SCO4747 | gene:17760112 | gene:17762396 | Conserved hypothetical protein SCC121.13c; Involved in DNA repair and RecF pathway recombination. | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | 0.441 |
SCO2510 | SCO4752 | gene:17760112 | gene:17762401 | Conserved hypothetical protein SCC121.13c; Involved in DNA repair and RecF pathway recombination. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.805 |
SCO2510 | SCO5791 | gene:17760112 | gene:17763451 | Conserved hypothetical protein SCC121.13c; Involved in DNA repair and RecF pathway recombination. | Putative tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.459 |
SCO3149 | SCO4752 | gene:17760766 | gene:17762401 | Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.834 |
SCO3149 | SCO5791 | gene:17760766 | gene:17763451 | Putative dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Putative tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.409 |
SCO3884 | SCO4752 | gene:17761511 | gene:17762401 | SCH24.06, conserved hypothetical protein, len: 170 aa; previously sequenced as TR:O54595 (EMBL:Y16311) Streptomyces coelicolor jag-like protein (170 aa). Similar to SW:JAG_BACSU (EMBL:Z14225), jag, Bacillus subtilis SpoIIIJ associated protein (208 aa), fasta scores; opt: 231 z-score: 268.4 E(): 1.1e-07, 31.7% identity in 139 aa overlap, and other jag homologs e.g. TR:O53598 (EMBL:AL021426) Mycobacterium tuberculosis hypothetical protein (187 aa) (62.7% identity in 169 aa overlap). | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.819 |
SCO4747 | SCO2510 | gene:17762396 | gene:17760112 | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Conserved hypothetical protein SCC121.13c; Involved in DNA repair and RecF pathway recombination. | 0.441 |
SCO4747 | SCO4750 | gene:17762396 | gene:17762399 | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). | 0.992 |
SCO4747 | SCO4751 | gene:17762396 | gene:17762400 | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | SC6G4.29, probable acetyltransferase, len: 177 aa; s imilar to e.g. RIMI_ECOLI ribosomal-protein-alanine acetyl transferase (148 aa), fasta scores; opt: 166 z-score: 257.4 E(): 4.5e-07, 33.3% identity in 120 aa overlap. Contains Pf am match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family, score 59.60, E-value 6.7e-14. | 0.628 |
SCO4747 | SCO4752 | gene:17762396 | gene:17762401 | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.997 |
SCO4747 | SCO5791 | gene:17762396 | gene:17763451 | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | Putative tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.928 |
SCO4750 | SCO4747 | gene:17762399 | gene:17762396 | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | 0.992 |
SCO4750 | SCO4751 | gene:17762399 | gene:17762400 | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). | SC6G4.29, probable acetyltransferase, len: 177 aa; s imilar to e.g. RIMI_ECOLI ribosomal-protein-alanine acetyl transferase (148 aa), fasta scores; opt: 166 z-score: 257.4 E(): 4.5e-07, 33.3% identity in 120 aa overlap. Contains Pf am match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family, score 59.60, E-value 6.7e-14. | 0.951 |
SCO4750 | SCO4752 | gene:17762399 | gene:17762401 | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.998 |
SCO4750 | SCO4753 | gene:17762399 | gene:17762402 | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). | Hypothetical protein; SC6G4.31, unknown, len: 90 aa. | 0.875 |
SCO4750 | SCO5791 | gene:17762399 | gene:17763451 | Conserved hypothetical protein; SC6G4.28, unknown, len: 217 aa; similar to hypothetical proteins from many organisms e.g. YEAZ_ECOLI (231 aa), fasta scores; opt: 257 z-score: 332.3 E(): 3e-11, 33.9% ide ntity in 221 aa overlapand Y098_MYCTU MTCY78.08 (211 aa), f asta scores; opt: 453 z-score: 467.2 E(): 9.3e-19, 48.1% i dentity in 212 aa overlap. Also some similarity to downstre am protein gcp (SC6G4.30; E(): 0.00023, 26.5% identity in 2 34 aa overlap). | Putative tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.486 |
SCO4751 | SCO4747 | gene:17762400 | gene:17762396 | SC6G4.29, probable acetyltransferase, len: 177 aa; s imilar to e.g. RIMI_ECOLI ribosomal-protein-alanine acetyl transferase (148 aa), fasta scores; opt: 166 z-score: 257.4 E(): 4.5e-07, 33.3% identity in 120 aa overlap. Contains Pf am match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family, score 59.60, E-value 6.7e-14. | Putative ATP/GTP binding protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). | 0.628 |