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SCO4764 protein (Streptomyces coelicolor) - STRING interaction network
"SCO4764" - SC6G4.42c, probable dehydrogenase, len: 257 aa in Streptomyces coelicolor
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
SCO4764SC6G4.42c, probable dehydrogenase, len- 257 aa; simi lar to many members of the short-chain dehydrogenases/reduc tases family e.g. TR-Q54190 (EMBL-D14040) S. galilaeus keto acyl reductase aknIII (261 aa), fasta scores; opt- 350 z-sc ore- 438.4 E()- 3.5e-17, 33.5% identity in 233 aa overlap. Contains Pfam match to entry PF00106 adh_short, Alcohol/oth er dehydrogenases, short chain type, score 158.00, E-value 1.6e-43; Belongs to the short-chain dehydrogenases/reductases (SDR) family (257 aa)    
Predicted Functional Partners:
SCO4765
Uncharacterized protein; SC6G4.43c, unknown, len- 233 aa; similar to hypothet ical proteins e.g. M. tuberculosis TR-P95151 (EMBL-Z83859) MTCY359.09 (251 aa), fasta scores; opt- 716 z-score- 609.7 E()- 1e-26, 54.4% identity in 215 aa overlap (233 aa)
              0.687
SCO3196
SCE22.13c, probable fructose-specific permease, len- 699 aa; similar to SW-PTFB_ECOLI (EMBL-M23196) Escherichia coli PTS system, fructose-specific IIBC component (EIIBC-fru) FruA 563 aa; fasta scores- opt- 1006 z-score- 1038.9 E()- 0; 43.7% identity in 583 aa overlap. Contains match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign. and possible hydrophobic membrane spanning regions in C-terminal domain (699 aa)
     
      0.538
SCO2651
Putative dehydrogenase/reductase (Putative secreted protein); SC8E4A.21c, possible dehydrogenase/reductase ( hypothetical protein), len- 245 aa; similar to TR-CAB52925 (EMBL-AL109949) Streptomyces coelicolor oxidoreductase SCJ11.40, 250 aa; fasta scores- opt- 717 z-score- 778.8 E()- 0; 47.6% identity in 250 aa overlap and to SW-LINX_PSEPA (EMBL-D23722) Pseudomonas paucimobilis 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase (EC 1.1.-.-) LinX, 250 aa; fasta scores- opt- 446 z-score- 488.9 E()- 8e-20; 34.3% identity in 248 aa overlap. Contains Pfam matches to entries PF00106 adh_s [...] (245 aa)
 
      0.523
SCO4763
Uncharacterized protein; SC6G4.41c, unknown, len- 413 aa (413 aa)
              0.519
SCO4766
SC6G4.44, probable transcriptional regulator, len- 306 aa; similar to many members of the lysR family e.g. CYNR_ ECOLI cyn operon transcriptional activator (299 aa), fasta scores; opt- 371 z-score- 524.3 E()- 5.8e-22, 30.3% identity in 307 aa overlap. Contains PS00044 Bacterial regulatory proteins, lysR family signature, helix-turn-helix motif at aa 18-39 (Score 1603, +4.65 SD) and Pfam match to entry PF0 0126 HTH_1, Bacterial regulatory helix-loop-helix proteins, lysR family, score 161.30, E-value 1.6e-44 (306 aa)
              0.494
SCO0111
SCJ11.40, probable oxidoreductase, len- 753 aa; similar to many egs. TR-O32457 (EMBL-D87924) ORF7 from the polyketide synthase cluster of Actinomadura hibisca (246 aa) fasta scores; opt- 480, z-score- 498.5, E()- 2.1e-20, (38.3% identity in 248 aa overlap) and TR-Q54810 (EMBL-L35560) reductase from the doxorubicin polyketide synthase cluster of Streptomyces peucetius (251 aa) fasta scores; opt- 408, z-score- 425.7, E()- 2.4e-16, (33.7% identity in 243 aa overlap). Contains Pfam matches to entry PF00106 adh_short, short chain dehydrogenase and to entry PF00678 adh_short_C2, Short chain [...] (250 aa)
      0.480
SCO2476
Putative dehydrogenase/reductase (Putative secreted protein); SC7A8.15c, probable dehydrogenase/reductase ( hypothetical protein), len- 247 aa; similar to TR-CAB52925 (EMBL-AL109949) Streptomyces coelicolor oxidoreductase SCJ11.40, 250 aa; fasta scores- opt- 591 z-score- 665.9 E()- 1.1e-29; 43.1% identity in 246 aa overlap and to SW-2BHD_STREX AC-P19992 Streptomyces exfoliatus (Streptomyces hydrogenans) 20-beta-hydroxysteroid dehydrogenase (EC 1.1.1.53), 25 aa; fasta scores- opt- 414 z-score- 469.7 E()- 9e-19; 36.1% identity in 249 aa overlap. Contains Pfam match to entry PF00106 adh_s [...] (247 aa)
      0.469
SCO4304
SCD95A.37, probable oxidoreductase, len- 249 aa; similar to TR-CAB71826 (EMBL-AL138662) Streptomyces coelicolor dehydrogenase/reductase SC8E4A.21c, 245 aa; fasta scores- opt- 757 z-score- 795.6 E()- 0; 50.0% identity in 250 aa overlap. Contains Pfam matches to entries PF00106 adh_short, short chain dehydrogenase and PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus and match to Prosite entry PS00061 Short-chain dehydrogenases/reductases family signature (249 aa)
      0.457
SCO7389
SC10G8.16, possible oxidoreductase, len- 292 aa. Similar to many including- Streptomyces clavuligerus TR-O54197(EMBL-AJ000671) clavulanate-9-aldehyde reductase (247 aa), fasta scores opt- 352 z-score- 389.3 E()- 2.9e-14 33.0% identity in 221 aa overlap and Streptomyces coelicolor TR-CAB59666(EMBL-AL132674) probable oxidoreductase, SCE87.21c (297 aa), fasta scores opt- 931 z-score- 1011.4 E()-0 52.8% identity in 286 aa overlap. Contains a Prosite hit PS00061 Short-chain dehydrogenases/reductases family signature and a Pfam match to entry PF00106 adh_short, short chain dehydrogenase (292 aa)
 
     
  0.415
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor, Streptomyces coelicolor A3(2)
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