STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4940SCK13.32, possible tetR-family transcriptional regulator, len: 200 aa; similar to TR:Q9KZX2 (EMBL:AL353815) Streptomyces coelicolor putative transcriptional regulator SCD6.32c, 200 aa; fasta scores: opt: 183 z-score: 230.1 E(): 2.8e-05; 28.3% identity in 159 aa overlap. Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family and possible helix-turn-helix motif at residues 33..54 (+4.53 SD). (200 aa)    
Predicted Functional Partners:
SCO4939
Hypothetical protein SCK31.31c; SCK13.31c, unknown, len: 260 aa.
 
     0.870
SCO6420
Putative DNA-binding protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
  
 0.698
SCO6046
Hypothetical protein; SC1B5.06c, unknown, len: 249 aa.
       0.560
SCO5638
SC6A9.29, probable integral membrane protein, len: 295 aa; this ORF has atypically low GC bias in FramePlot.
  
     0.478
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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