STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO4955Putative ATP/GTP-binding protein; 2SCK31.15c, hypothetical protein, len: 395 aa; similar to TR:Q9X8V7 (EMBL:AL078610) Streptomyces coelicolor hypothetical 43.9 kDa protein SCH35.49c, 410 aa; fasta scores: opt: 1788 z-score: 1973.1 E(): 0; 63.8% identity in 398 aa overlap. Contains match to Prosite entry PS00017 ATP/GTP-binding site motif A (P-loop). (395 aa)    
Predicted Functional Partners:
SCO7637
SC10F4.10c, secreted endoglucanase, len: 486 aa; highly similar to SW:GUNA_STRLI (EMBL:M82807) Streptomyces lividans endoglucanase CelA precursor (EC 3.2.1.4) CelA, 459 aa; fasta scores: opt: 2977 z-score: 3136.1 E(): 0; 97.4% identity in 461 aa overlap. Contains Pfam matches to entries PF00553 CBD_2, Cellulose binding domain and PF00150 cellulase, Cellulase (glycosyl hydrolase family 5) and matches to Prosite entries PS00561 Cellulose-binding domain, bacterial type and PS00659 Glycosyl hydrolases family 5 signature. Also contains possible N-terminal region signal peptide sequence.
    
 
 0.689
SCO4956
Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
       0.522
SCO4954
Hypothetical protein 2SCK31.14c; 2SCK31.14c, unknown, len: 197 aa.
       0.494
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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