node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0560 | SCO0999 | gene:17758143 | gene:17758582 | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.755 |
SCO0560 | SCO2369 | gene:17758143 | gene:17759968 | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | SCC8A.27c, possible thiol-specific antioxidant protein, len: 152 aa; similar to many e.g. SW:O24364 (BAS1_SPIOL) 2-cys peroxiredoxin Bas1 precursor from Spinacia oleracea (Spinach) (265 aa) fasta scores; opt: 352, z-score: 450.7, E(): 1.2e-17, 39.9% identity in 158 aa overlap and SW:Q10520 (Y01J_MYCTU) hypothetical protein from Mycobacterium tuberculosis (153 aa) fasta scores; opt: 507, z-score: 648.2, E(): 1.2e-28, 48.7% identity in 150 aa overlap. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | 0.418 |
SCO0560 | SCO5031 | gene:17758143 | gene:17762680 | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.711 |
SCO0560 | SCO5032 | gene:17758143 | gene:17762681 | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | SCK7.05c, ahpC, alkyl hydroperoxide reductase, len:184 aa; identical to previously seqeunced TR:Q9RN72 (EMBL:AF186371) Streptomyces coelicolor A3(2) AhpC, 184 aa. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | 0.828 |
SCO0560 | SCO5033 | gene:17758143 | gene:17762682 | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | SCK7.06, oxyR, hydrogen peroxide sensing regulator, len: 312 aa; identical to previously sequenced TR:Q9RN71 (EMBL:AF186371) Streptomyces coelicolor A3(2) hydrogen peroxide sensing regulator OxyR, 313 aa. Contains Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family and match to Prosite entry S00044 Bacterial regulatory proteins, lysR family signature. Also contains possible helix-turn-helix motif at residues 23..44 (+3.89 SD); Belongs to the LysR transcriptional regulatory family. | 0.686 |
SCO0999 | SCO0560 | gene:17758582 | gene:17758143 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | 0.755 |
SCO0999 | SCO5031 | gene:17758582 | gene:17762680 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.477 |
SCO0999 | SCO5032 | gene:17758582 | gene:17762681 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | SCK7.05c, ahpC, alkyl hydroperoxide reductase, len:184 aa; identical to previously seqeunced TR:Q9RN72 (EMBL:AF186371) Streptomyces coelicolor A3(2) AhpC, 184 aa. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | 0.738 |
SCO1595 | SCO3023 | gene:17759188 | gene:17760638 | SCI35.17c, pheS, probable phenylalanyl-tRNA synthetase alpha chain, len: 373 aa; similar to many e.g. SYFA_ECOLI phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (327 aa), fasta scores; opt: 682 z-score: 1248.8 E(): 0, 43.1% identity in 343 aa overlap. Contains PS00179 and PS00339 Aminoacyl-transfer RNA synthetases class-II signatures 1 and 2. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.553 |
SCO1595 | SCO5031 | gene:17759188 | gene:17762680 | SCI35.17c, pheS, probable phenylalanyl-tRNA synthetase alpha chain, len: 373 aa; similar to many e.g. SYFA_ECOLI phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (327 aa), fasta scores; opt: 682 z-score: 1248.8 E(): 0, 43.1% identity in 343 aa overlap. Contains PS00179 and PS00339 Aminoacyl-transfer RNA synthetases class-II signatures 1 and 2. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.590 |
SCO2180 | SCO5031 | gene:17759777 | gene:17762680 | SC5F7.21, pdhL, probable dihydrolipoamide dehydrogenase, len: 486 aa; note possible downstream translational start sites. Similar to many prokaryote and eukaryote egs. TR:Q9Z6I5 (EMBL: AF047034) dihydrolipoamide dehydrogenase from Streptomyces seoulensis (462 aa) fasta scores; opt: 2780, z-score: 3088.0, E(): 0, (90.3% identity in 462 aa overlap), TR:Q54101 (EMBL:L38646) NADH ferredoxin oxidoreductase from Saccharopolyspora erythraea (456 aa) fasta scores; opt: 1918, z-score: 2131.8, E(): 0, (64.2% identity in 452 aa overlap) and SW:DLDH_PEA dihydrolipoamide dehydrogenase from Pisum sa [...] | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.710 |
SCO2180 | SCO5032 | gene:17759777 | gene:17762681 | SC5F7.21, pdhL, probable dihydrolipoamide dehydrogenase, len: 486 aa; note possible downstream translational start sites. Similar to many prokaryote and eukaryote egs. TR:Q9Z6I5 (EMBL: AF047034) dihydrolipoamide dehydrogenase from Streptomyces seoulensis (462 aa) fasta scores; opt: 2780, z-score: 3088.0, E(): 0, (90.3% identity in 462 aa overlap), TR:Q54101 (EMBL:L38646) NADH ferredoxin oxidoreductase from Saccharopolyspora erythraea (456 aa) fasta scores; opt: 1918, z-score: 2131.8, E(): 0, (64.2% identity in 452 aa overlap) and SW:DLDH_PEA dihydrolipoamide dehydrogenase from Pisum sa [...] | SCK7.05c, ahpC, alkyl hydroperoxide reductase, len:184 aa; identical to previously seqeunced TR:Q9RN72 (EMBL:AF186371) Streptomyces coelicolor A3(2) AhpC, 184 aa. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | 0.586 |
SCO2369 | SCO0560 | gene:17759968 | gene:17758143 | SCC8A.27c, possible thiol-specific antioxidant protein, len: 152 aa; similar to many e.g. SW:O24364 (BAS1_SPIOL) 2-cys peroxiredoxin Bas1 precursor from Spinacia oleracea (Spinach) (265 aa) fasta scores; opt: 352, z-score: 450.7, E(): 1.2e-17, 39.9% identity in 158 aa overlap and SW:Q10520 (Y01J_MYCTU) hypothetical protein from Mycobacterium tuberculosis (153 aa) fasta scores; opt: 507, z-score: 648.2, E(): 1.2e-28, 48.7% identity in 150 aa overlap. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | 0.418 |
SCO2369 | SCO5031 | gene:17759968 | gene:17762680 | SCC8A.27c, possible thiol-specific antioxidant protein, len: 152 aa; similar to many e.g. SW:O24364 (BAS1_SPIOL) 2-cys peroxiredoxin Bas1 precursor from Spinacia oleracea (Spinach) (265 aa) fasta scores; opt: 352, z-score: 450.7, E(): 1.2e-17, 39.9% identity in 158 aa overlap and SW:Q10520 (Y01J_MYCTU) hypothetical protein from Mycobacterium tuberculosis (153 aa) fasta scores; opt: 507, z-score: 648.2, E(): 1.2e-28, 48.7% identity in 150 aa overlap. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.618 |
SCO2369 | SCO5032 | gene:17759968 | gene:17762681 | SCC8A.27c, possible thiol-specific antioxidant protein, len: 152 aa; similar to many e.g. SW:O24364 (BAS1_SPIOL) 2-cys peroxiredoxin Bas1 precursor from Spinacia oleracea (Spinach) (265 aa) fasta scores; opt: 352, z-score: 450.7, E(): 1.2e-17, 39.9% identity in 158 aa overlap and SW:Q10520 (Y01J_MYCTU) hypothetical protein from Mycobacterium tuberculosis (153 aa) fasta scores; opt: 507, z-score: 648.2, E(): 1.2e-28, 48.7% identity in 150 aa overlap. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | SCK7.05c, ahpC, alkyl hydroperoxide reductase, len:184 aa; identical to previously seqeunced TR:Q9RN72 (EMBL:AF186371) Streptomyces coelicolor A3(2) AhpC, 184 aa. Contains Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family. | 0.448 |
SCO3023 | SCO1595 | gene:17760638 | gene:17759188 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | SCI35.17c, pheS, probable phenylalanyl-tRNA synthetase alpha chain, len: 373 aa; similar to many e.g. SYFA_ECOLI phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (327 aa), fasta scores; opt: 682 z-score: 1248.8 E(): 0, 43.1% identity in 343 aa overlap. Contains PS00179 and PS00339 Aminoacyl-transfer RNA synthetases class-II signatures 1 and 2. | 0.553 |
SCO3023 | SCO5031 | gene:17760638 | gene:17762680 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.481 |
SCO4224 | SCO5031 | gene:17761868 | gene:17762680 | Hypothetical protein; 2SCD46.38c, unknown, len: 421aa. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.483 |
SCO4835 | SCO5031 | gene:17762484 | gene:17762680 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | 0.487 |
SCO5031 | SCO0560 | gene:17762680 | gene:17758143 | Alkyl hydroperoxide reductase system hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. | Catalase/peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. | 0.711 |