STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO5069SCBAC20F6.12, possible oxidoreductase, len: 318 aa; similar to many oxidoreductases/dehydratases, e.g. TR:Q9WX20 (EMBL:AL079345) Streptomyces coelicolor putative dehydrogenase SCE68.12c, 318 aa; fasta scores: opt: 998 Z-score: 1062.9 bits: 204.9 E(): 1.3e-51; 52.997% identity in 317 aa overlap. Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. (318 aa)    
Predicted Functional Partners:
SCO5068
SCBAC20F6.11c, possible tetR-family transcriptional regulator, len: 199 aa; similar to many actinomycetes putative tetR-family transcriptional regulators, e.g. TR:Q9RJL5 (EMBL:AL121849) Streptomyces coelicolor putative tetR-family transcriptional regulator SCF6.16, 194 aa; fasta scores: opt: 419 Z-score: 483.9 bits: 96.4 E(): 2.3e-19; 38.095% identity in 189 aa overlap. Contains Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family and possible helix-turn-helix motif at residues 36..57 (+4.64 SD).
       0.533
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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