STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO5397SC8F4.01c, large Ala/Glu-rich protein, len: 1326 aa; hydrophilic with strong potential for coiled-coil structure throughout. (1326 aa)    
Predicted Functional Partners:
SCO5396
2SC6G5.40c, probable cellulose-binding protein, len: 310aa; strongly similar to TR: (EMBL:) AbpS avicel-binding protein from Streptomyces reticuli (311 aa) fasta scores; opt: 1777, z-score: 1598.0, E(): 0, 93.2% identity in 311 aa overlap. Contains a possible membrane-spanning hydrophobic region close to the N-terminus and possible coiled-coil regions throughout.
 
   
 0.985
SCO3114
SCE41.23c, conserved hypothetical protein, len: 298 aa; similar to TR:O07481 (EMBL:Z97071) Streptomyces reticuli AbpS protein, 311 aa; fasta scores: opt: 482 z-score: 473.6 E(): 7.1e-19; 35.0% identity in 294 aa overlap. Contains various coiled-coil regions at approx. residues 42..60 and 207..251.
  
   
 0.963
SCO4162
SCD84.29, possible integral membrane protein, len: 437 aa. High content in alanine, proline, glycine and glutamine amino acid residues. Contains possible hydrophobic membrane spanning domains in C-terminal region and degenerate amino acid repeat: 6x (R/P/Q)YDP(N/G) in N-terminal region.
 
    0.788
SCO5394
2SC6G5.38c, possible ABC transporter integral membrane subunit, len: 256aa; similar to many membrane proteins of eg. TR:O86630 (EMBL:AL031155) probable integral membrane protein from Streptomyces coelicolor (279 aa) fasta scores; opt: 504, z-score: 572.6, E(): 2e-24, 37.6% identity in 258 aa overlap.. Contains possible membrane-spanning hydrophobic regions and lies immediately downstream of a possible ABC transporter ATP-binding subunit.
 
   0.782
SCO3115
Hypothetical protein SCE41.24c; SCE41.24c, unknown, len: 889 aa. High content in alanine, glycine and proline amino acid residues. Contains 20x degenerate repeat: (G/P/A/N)P(G/P/A).
 
     0.777
SCO2578
Putative membrane protein; SCC123.16c, possible membrane protein, len: 592 aa. Contains a possible membrane spanning hydrophobic domain. The protein is rich in the amino acid Gln and has a notable repeat region with 6x QQ(G/Y) between residues 53..84.
  
     0.773
SCO3676
SCH35.48c, possible integral membrane protein, len: 350aa; Contains possible membrane spanning hydrophobic regions in the C-terminal half and a hydrophobic N-terminal half.
  
     0.773
SCO3840
Hypothetical protein; SCH69.10c, unknown, len: 271aa; similar to TR:P74322 (EMBL:D90914) from Synechocystis sp. PCC6803 (228 aa) fasta scores; opt: 238, z-score: 277.0, E(): 4.2e-08, (26.6% identity in 259 aa overlap). Contains possible coiled-coil at 30-40aa.
  
    0.773
SCO2356
SCC8A.14, possible membrane protein, len: 467aa; contains a possible membrane-spanning hydrophobic region close to the N-terminus.
 
    0.770
SCO3350
Hypothetical protein; SCE94.01c, partial CDS unknown, alanine-rich protein, len: >503aa; SCE7.17c, partial CDS, proline-rich protein, len: >129aa.
  
    0.770
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.