node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO3322 | SCO4366 | gene:17760941 | gene:17762011 | SCE68.20, putative membrane protein, len: 298 aa; unknown function, similar to TR:O33611 (EMBL:AB004855) Streptomyces cyaneus hypothetical protein (277 aa), fasta scores; opt: 463 z-score: 536.3 E(): 1.5e-22, 34.2% identity in 269 aa overlap. C-terminus similar to other hypothetical proteins e.g. SW:YV32_MYCTU (EMBL:Z77162) from Mycobacterium tuberculosis (373 aa) (57.8% identity in 256 aa overlap) and SCH5.21 (EMBL:AL035636) S.coelicolor hypothetical protein (268 aa) (36.3% identity in 267 aa overlap). Contains possible hydrophobic membrane spanning region at C-terminal domain. | Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.692 |
SCO3322 | SCO5510 | gene:17760941 | gene:17763162 | SCE68.20, putative membrane protein, len: 298 aa; unknown function, similar to TR:O33611 (EMBL:AB004855) Streptomyces cyaneus hypothetical protein (277 aa), fasta scores; opt: 463 z-score: 536.3 E(): 1.5e-22, 34.2% identity in 269 aa overlap. C-terminus similar to other hypothetical proteins e.g. SW:YV32_MYCTU (EMBL:Z77162) from Mycobacterium tuberculosis (373 aa) (57.8% identity in 256 aa overlap) and SCH5.21 (EMBL:AL035636) S.coelicolor hypothetical protein (268 aa) (36.3% identity in 267 aa overlap). Contains possible hydrophobic membrane spanning region at C-terminal domain. | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | 0.463 |
SCO4366 | SCO3322 | gene:17762011 | gene:17760941 | Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | SCE68.20, putative membrane protein, len: 298 aa; unknown function, similar to TR:O33611 (EMBL:AB004855) Streptomyces cyaneus hypothetical protein (277 aa), fasta scores; opt: 463 z-score: 536.3 E(): 1.5e-22, 34.2% identity in 269 aa overlap. C-terminus similar to other hypothetical proteins e.g. SW:YV32_MYCTU (EMBL:Z77162) from Mycobacterium tuberculosis (373 aa) (57.8% identity in 256 aa overlap) and SCH5.21 (EMBL:AL035636) S.coelicolor hypothetical protein (268 aa) (36.3% identity in 267 aa overlap). Contains possible hydrophobic membrane spanning region at C-terminal domain. | 0.692 |
SCO4366 | SCO5510 | gene:17762011 | gene:17763162 | Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | 0.705 |
SCO4366 | SCO5513 | gene:17762011 | gene:17763165 | Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | SC8D9.25, ilvN, acetolactate synthase small subunit, len: 174 aa; high level of similarity to many e.g. TR:Q59817 (EMBL:L39268) IlvN, acetolactate synthase small subunit from the ilvBNC gene cluster of Streptomyces avermitilis (176 aa) fasta scores; opt: 884, z-score: 1056.9, E(): 0, (86.4% identity in 176 aa overlap). | 0.439 |
SCO5507 | SCO5508 | gene:17763159 | gene:17763160 | Hypothetical protein; SC8D9.19, unknown, len: 69 aa. | SC8D9.20c, possible oxidoreductase, len: 447aa; similar to many of undefined function and SW:DHGB_ACICA glucose dehydrogenase-B from Acinetobacter calcoaceticus (478 aa) fasta scores; opt: 247, z-score: 253.8, E(): 7.9e-07, (27.4% identity in 369 aa overlap). | 0.560 |
SCO5507 | SCO5509 | gene:17763159 | gene:17763161 | Hypothetical protein; SC8D9.19, unknown, len: 69 aa. | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | 0.560 |
SCO5507 | SCO5510 | gene:17763159 | gene:17763162 | Hypothetical protein; SC8D9.19, unknown, len: 69 aa. | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | 0.560 |
SCO5508 | SCO5507 | gene:17763160 | gene:17763159 | SC8D9.20c, possible oxidoreductase, len: 447aa; similar to many of undefined function and SW:DHGB_ACICA glucose dehydrogenase-B from Acinetobacter calcoaceticus (478 aa) fasta scores; opt: 247, z-score: 253.8, E(): 7.9e-07, (27.4% identity in 369 aa overlap). | Hypothetical protein; SC8D9.19, unknown, len: 69 aa. | 0.560 |
SCO5508 | SCO5509 | gene:17763160 | gene:17763161 | SC8D9.20c, possible oxidoreductase, len: 447aa; similar to many of undefined function and SW:DHGB_ACICA glucose dehydrogenase-B from Acinetobacter calcoaceticus (478 aa) fasta scores; opt: 247, z-score: 253.8, E(): 7.9e-07, (27.4% identity in 369 aa overlap). | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | 0.875 |
SCO5508 | SCO5510 | gene:17763160 | gene:17763162 | SC8D9.20c, possible oxidoreductase, len: 447aa; similar to many of undefined function and SW:DHGB_ACICA glucose dehydrogenase-B from Acinetobacter calcoaceticus (478 aa) fasta scores; opt: 247, z-score: 253.8, E(): 7.9e-07, (27.4% identity in 369 aa overlap). | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | 0.632 |
SCO5509 | SCO5507 | gene:17763161 | gene:17763159 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | Hypothetical protein; SC8D9.19, unknown, len: 69 aa. | 0.560 |
SCO5509 | SCO5508 | gene:17763161 | gene:17763160 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | SC8D9.20c, possible oxidoreductase, len: 447aa; similar to many of undefined function and SW:DHGB_ACICA glucose dehydrogenase-B from Acinetobacter calcoaceticus (478 aa) fasta scores; opt: 247, z-score: 253.8, E(): 7.9e-07, (27.4% identity in 369 aa overlap). | 0.875 |
SCO5509 | SCO5510 | gene:17763161 | gene:17763162 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | 0.672 |
SCO5509 | SCO5511 | gene:17763161 | gene:17763163 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | SC8D9.23, possible large membrane associated phophodiesterase, len: 1108aa; the first 400aa of this protein appear to contain several potential membrane spanning regions. The remainder shows similarity to several eg. TR:O87378 (EMBL:AF052519) C-DI-GMP phophodiesterase A from Acetobacter xylinum (740 aa) fasta scores; opt: 683, z-score: 565.4, E(): 3.4e-24, (27.3% identity in 645 aa overlap). Also similar to a nearby gene on the same cosmid (SC8D9.07) fasta scores; opt: 736, z-score: 499.5, E(): 5.6e-23, (32.4% identity in 728 aa overlap). Contains Pfam match to entries PF00989 PAS, PAS [...] | 0.690 |
SCO5509 | SCO5512 | gene:17763161 | gene:17763164 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | SC8D9.24, ilvB, acetolactate synthase, len: 613aa; high level of similarity to many eg. TR:Q59816 (EMBL:L39268) ilvB, acetolactate synthase from the ilvBNC gene cluster of Streptomyces avermitilis (617 aa) fasta scores; opt: 3558, z-score: 3786.3, E(): 0, (87.2% identity in 619 aa overlap). Contains PS00187 Thiamine pyrophosphate enzymes signature and Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzymes, score 899.00, E-value 3.2e-278. | 0.651 |
SCO5509 | SCO5514 | gene:17763161 | gene:17763166 | SC8D9.21c, probable oxidoreductase, len: 447aa; similar to many both prokaryotic and eukaryotic egs. SW:A115_TOBAC auxin induced protein (probable oxidoreductase) from Nicotiana tabacum (common tobacco) (307 aa) fasta scores; opt: 391, z-score: 456.6, E(): 4e-18, (36.7% identity in 289 aa overlap) and TR:O07152 (EMBL:Z96801) putative oxidoreductase from Mycobacterium leprae (306 aa) fasta scores; opt: 336, z-score: 393.5, E(): 1.3e-14, (30.8% identity in 295 aa overlap). Contains Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase family, score 33.70, E-value 4.6e-09. | Acetolactate synthase small subunit; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.417 |
SCO5510 | SCO3322 | gene:17763162 | gene:17760941 | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | SCE68.20, putative membrane protein, len: 298 aa; unknown function, similar to TR:O33611 (EMBL:AB004855) Streptomyces cyaneus hypothetical protein (277 aa), fasta scores; opt: 463 z-score: 536.3 E(): 1.5e-22, 34.2% identity in 269 aa overlap. C-terminus similar to other hypothetical proteins e.g. SW:YV32_MYCTU (EMBL:Z77162) from Mycobacterium tuberculosis (373 aa) (57.8% identity in 256 aa overlap) and SCH5.21 (EMBL:AL035636) S.coelicolor hypothetical protein (268 aa) (36.3% identity in 267 aa overlap). Contains possible hydrophobic membrane spanning region at C-terminal domain. | 0.463 |
SCO5510 | SCO4366 | gene:17763162 | gene:17762011 | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.705 |
SCO5510 | SCO5507 | gene:17763162 | gene:17763159 | SC8D9.22, probable dehydrogenase, len: 313aa; similar to many both eukaryotic and prokaryotic egs. SW:FDH_SOLTU NAD-dependent formate dehydrogenase from the mitochondria of Solanum tuberosum (potato) (379 aa) fasta scores; opt: 372, z-score: 413.2, E(): 1e-15, (29.9% identity in 278 aa overlap) and SW:SERA_BACSU D-3-phosphoglycerate dehydrogenase from Bacillus subtilis (525 aa) fasta scores; opt: 348, z-score: 384.9, E(): 3.9e-14, (32.4% identity in 256 aa overlap). Contains PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3 and Pfam match to entry PF00389 2-Hacid_DH, D [...] | Hypothetical protein; SC8D9.19, unknown, len: 69 aa. | 0.560 |