SCO5953 protein (Streptomyces coelicolor) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SCO5953

SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74. (913 aa)

Predicted Functional Partners:

SCO4801

0.910

SCO4422

0.881

SCO4675

0.872

SCO5952

0.827

SCO1664

0.825

SCO4676

0.666

SCO1501

0.646

SCO7600

0.646

SCO6818

0.636

SCO4654

0.582

Your Current Organism:

Streptomyces coelicolor

NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SCO1501	SCO4654	gene:17759087	gene:17762303	Alanine tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.431
SCO1501	SCO5953	gene:17759087	gene:17763613	Alanine tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.646
SCO1664	SCO4801	gene:17759257	gene:17762450	SCI52.06, conserved hypothetical protein, len: 265 aa; similar to TR:O06242 (EMBL:Z95388) Mycobacterium tuberculosis hypothetical 28.3 kDa protein MTCY270.35, 262 aa; fasta scores: opt: 495 Z-score: 595.6 bits: 117.9 E(): 1.4e-25; 50.951% identity in 263 aa overlap.	Hypothetical protein SCD63A.12c; SCD63A.12c, unknown, len: 606 aa. High content in alanine amino acid residues.	0.983
SCO1664	SCO5953	gene:17759257	gene:17763613	SCI52.06, conserved hypothetical protein, len: 265 aa; similar to TR:O06242 (EMBL:Z95388) Mycobacterium tuberculosis hypothetical 28.3 kDa protein MTCY270.35, 262 aa; fasta scores: opt: 495 Z-score: 595.6 bits: 117.9 E(): 1.4e-25; 50.951% identity in 263 aa overlap.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.825
SCO4422	SCO5953	gene:17762067	gene:17763613	SC6F11.20, possible hydrolase, len: 252 aa; similar to TR:Q9X7R7 (EMBL:AL049863) Streptomyces coelicolor putative hydrolase SC5H1.09c, 265 aa; fasta scores: opt: 465 z-score: 555.8 E(): 1.9e-23; 40.1% identity in 252 aa overlap.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.881
SCO4654	SCO1501	gene:17762303	gene:17759087	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Alanine tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	0.431
SCO4654	SCO4801	gene:17762303	gene:17762450	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Hypothetical protein SCD63A.12c; SCD63A.12c, unknown, len: 606 aa. High content in alanine amino acid residues.	0.906
SCO4654	SCO5953	gene:17762303	gene:17763613	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.582
SCO4654	SCO6818	gene:17762303	gene:17764477	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Putative phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.	0.445
SCO4654	SCO7600	gene:17762303	gene:17765260	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	SC7H9.12c, possible alanyl tRNA synthetase, len: 404 aa; similar to N-terminal region of SW:SYA_THIFE (EMBL:X95571) Thiobacillus ferrooxidans alanyl-tRNA-synthetase (EC 6.1.1.7) AlaS, 877 aa; fasta scores: opt: 728 z-score: 825.4 E(): 0; 37.4% identity in 425 aa overlap. Contains Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A) and matches to Prosite entries PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2 and PS00017 ATP/GTP-binding site motif A (P-loop).	0.544
SCO4675	SCO4676	gene:17762324	gene:17762325	SCD40A.21c, hypothetical protein, len: 302 aa; similar to TR:Q9XD94 (EMBL:AF106004) Streptomyces coelicolor hypothetical 34.1 kD protein, 304 aa; fasta scores: opt: 850 z-score: 992.1 E(): 0; 45.0% identity in 300 aa overlap. Contains match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign.	Hypothetical protein; SCD31.01c, unknown (fragment), len: >147 aa; SCD40A.22c, unknown (fragment), len: > 176 aa.	0.911
SCO4675	SCO5953	gene:17762324	gene:17763613	SCD40A.21c, hypothetical protein, len: 302 aa; similar to TR:Q9XD94 (EMBL:AF106004) Streptomyces coelicolor hypothetical 34.1 kD protein, 304 aa; fasta scores: opt: 850 z-score: 992.1 E(): 0; 45.0% identity in 300 aa overlap. Contains match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.872
SCO4676	SCO4675	gene:17762325	gene:17762324	Hypothetical protein; SCD31.01c, unknown (fragment), len: >147 aa; SCD40A.22c, unknown (fragment), len: > 176 aa.	SCD40A.21c, hypothetical protein, len: 302 aa; similar to TR:Q9XD94 (EMBL:AF106004) Streptomyces coelicolor hypothetical 34.1 kD protein, 304 aa; fasta scores: opt: 850 z-score: 992.1 E(): 0; 45.0% identity in 300 aa overlap. Contains match to Prosite entry PS00402 Binding-protein-dependent transport systems inner membrane comp sign.	0.911
SCO4676	SCO5953	gene:17762325	gene:17763613	Hypothetical protein; SCD31.01c, unknown (fragment), len: >147 aa; SCD40A.22c, unknown (fragment), len: > 176 aa.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.666
SCO4801	SCO1664	gene:17762450	gene:17759257	Hypothetical protein SCD63A.12c; SCD63A.12c, unknown, len: 606 aa. High content in alanine amino acid residues.	SCI52.06, conserved hypothetical protein, len: 265 aa; similar to TR:O06242 (EMBL:Z95388) Mycobacterium tuberculosis hypothetical 28.3 kDa protein MTCY270.35, 262 aa; fasta scores: opt: 495 Z-score: 595.6 bits: 117.9 E(): 1.4e-25; 50.951% identity in 263 aa overlap.	0.983
SCO4801	SCO4654	gene:17762450	gene:17762303	Hypothetical protein SCD63A.12c; SCD63A.12c, unknown, len: 606 aa. High content in alanine amino acid residues.	DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.906
SCO4801	SCO5953	gene:17762450	gene:17763613	Hypothetical protein SCD63A.12c; SCD63A.12c, unknown, len: 606 aa. High content in alanine amino acid residues.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.910
SCO5952	SCO5953	gene:17763612	gene:17763613	SC7H1.22, putative membrane protein, len: 250 aa. Contains possible hydrophobic membrane spanning regions.	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	0.827
SCO5953	SCO1501	gene:17763613	gene:17759087	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	Alanine tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.	0.646
SCO5953	SCO1664	gene:17763613	gene:17759257	SC7H1.23, putative membrane protein, len: 913 aa; weakly similar to many members of the eukaryotic beta-transducin family e.g. YA3A_SCHPO Q09715 hypothetical Trp-Asp repeats containing protein (614 aa), fasta scores; opt: 139 z-score: 352.6 E(): 1.9e-12, 28.8% identity in 250 aa overlap. Contains possible membrane spanning domain around aa 200 and 3x Pfam match to entry G-beta PF00400, WD domain, G-beta repeats, scores; 27.34, 28.55 and 25.74.	SCI52.06, conserved hypothetical protein, len: 265 aa; similar to TR:O06242 (EMBL:Z95388) Mycobacterium tuberculosis hypothetical 28.3 kDa protein MTCY270.35, 262 aa; fasta scores: opt: 495 Z-score: 595.6 bits: 117.9 E(): 1.4e-25; 50.951% identity in 263 aa overlap.	0.825

page 1 of 2

Server load: medium (46%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2023

Credits

Access

Info

About