STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO6009SC7B7.06, probable solute-binding protein of transmembrane transport system, len: 403 aa; similar to many eg. XYLF_ECOLI P37387 d-xylose-binding periplasmic protein precursor (330 aa), fasta scores; opt: 619 z-score: 573.4 E(): 8.9e-25, 35.7% identity in 325 aa overlap. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. (371 aa)    
Predicted Functional Partners:
SCO6011
SC7B7.08, probable ABC-type trans- membrane transport protein, len: 430 aa; similar to many others of the ARAH/RBSC subfamily of the binding-protein dependent transport systems eg. XYLH_ECOLI P37389 xylose transport permease protein xylH (393 aa), fasta scores; opt: 695 z-score: 690.3 E(): 2.7e-31, 34.2% identity in 377 aa overlap. Possible alternative start site 33 aa downstream.
 
 0.993
SCO6010
SC7B7.07, probable ABC-transport system ATP binding protein, len: 260 aa; similar to many eg. XYLG_ECOLI P37388 d-xylose transport atp-binding protein (513 aa), fasta scores; opt: 567 z-score: 580.0 E(): 3.8e-25, 36.5% identity in 255 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signature. Possible alternative start 9 bp upstream.
 
 0.979
SCO3667
SCH44.07c, probable secreted solute-binding protein, len: 372 aa; similar to TR:O50503 (EMBL:AL009199) Streptomyces coelicolor possible solute-binding protein SC7B7.06, 371 aa; fasta scores: opt: 1441 z-score: 1539.7 E(): 0; 60.6% identity in 376 aa overlap and to SW:XYLF_ECOLI (EMBL:U00039) Escherichia coli D-xylose-binding periplasmic protein precursor XylF, 330 aa; fasta scores: opt: 559 z-score: 602.9 E(): 4.1e-26; 34.3% identity in 318 aa overlap. Contains Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family and corr [...]
  
  
 
0.902
SCO2406
SC4A7.34, probable sugar transport permease, len: 414 aa; similar to TR:AAD45714 (EMBL:AF160811) Bacillus stearothermophilus L-arabinose membrane permease AraH, 407 aa; fasta scores: opt: 1448 z-score: 1515.1 E(): 0; 56.9% identity in 385 aa overlap and to SW:XYLH_HAEIN (EMBL:U32791) Haemophilus influenzae xylose transport permease protein XylH, 375 aa; fasta scores: opt: 970 z-score: 1017.9 E(): 0; 42.6% identity in 376 aa overlap.
  
 0.830
SCO6006
Probable transmembrane transport protein; Part of the ABC transporter complex NgcEFG-MsiK involved in N,N'-diacetylchitobiose ((GlcNAc)2) uptake. Responsible for the translocation of the substrate across the membrane. Belongs to the binding-protein-dependent transport system permease family.
     
 0.801
SCO2405
SC4A7.24, probable sugar-transport ATP binding protein, len: 513 aa; similar to TR:AAD45713 (EMBL:AF160811) Bacillus stearothermophilus L-arabinose transport, ATP binding protein AraG, 513 aa; fasta scores: opt: 2220 z-score: 2417.4 E(): 0; 65.5% identity in 510 aa overlap and to SW:ALSA_ECOLI (EMBL:U14003) Escherichia coli D-allose transport ATP-binding protein AlsA, 510 aa; fasta scores: opt: 1200 z-score: 1308.3 E(): 0; 40.7% identity in 514 aa overlap. Contains two Pfam matches to entry PF00005 ABC_tran, ABC transporter and two matches to Prosite entries PS00017 ATP/GTP-binding sit [...]
  
 0.787
SCO0809
SCF43.20c. possible ABC transporter permease, len: 337 aa. Similar to many permeases e.g. Bacillus subtilis SW:RBSC_BACSU(EMBL:Z25798) ribose transport system permease protein RbsC (323 aa), fasta scores opt: 561 z-score: 603.2 E(): 3.3e-26 33.9% identity in 295 aa overlap. Also similar to the adjoining CDS, SCF43.21c, possible ABC transporter permease (346 aa), fasta scores opt: 545 z-score: 528.3 E(): 5e-24 33.4% identity in 335 aa overlap. Contains multiple possible membrane spanning hydrophobic domains.
 
   
 0.766
SCO0810
SCF43.21c. possible ABC transporter permease, len: 346 aa. Similar to many permeases e.g. Bacillus subtilis SW:RBSC_BACSU(EMBL:Z25798) ribose transport system permease protein RbsC (323 aa), fasta scores opt: 591 z-score: 644.0 E(): 1.7e-28 33.4% identity in 302 aa overlap and Escherichia coli SW:RBSC_ECOLI(EMBL:L10328) ribose transport system permease protein RbsC (321 aa), fasta scores opt: 596 z-score: 649.4 E(): 8.6e-29 34.5% identity in 304 aa overlap. Also similar to the adjoining CDS, SCF43.20c, possible ABC transporter permease (346 aa), fasta scores opt: 545 z-score: 528.3 E() [...]
 
   
 0.763
SCO6568
SC3F9.03, ABC transporter integral membrane protein, len: 339 aa; similar to many involved in sugar transport e.g. RBSC_BACSU ribose transport system permease protein (323 aa), fasta scores; opt: 700 z-score: 958.9 E(): 0, 39.5%identity in 314 aa overlap.
 
   
 0.762
SCO6008
SC7B7.05, probable transcriptional repressor protein, len 403 aa; similar to many eg. XYLR_ANATH Q44406 xylose repressor from Anaerocellum thermophilum (399 aa), fasta scores; opt: 548 z-score: 767.3 E(): 0, 33.1% identity in 393 aa overlap. Contains PS01125 ROK family signature and helix-turn-helix motif at aa positions 29-50 (Score 2016, +6.05 SD).
 
   
 0.739
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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