node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO1515 | SCO1516 | gene:17759101 | gene:17759102 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.999 |
SCO1515 | SCO1517 | gene:17759101 | gene:17759103 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | SCL2.07c, possible secreted protein, len: 169 aa; similar to SW:YP88_MYCLE (EMBL:AL023591) Mycobacterium leprae hypothetical protein MCLB1259.04, 114 aa; fasta scores: opt: 205 z-score: 231.1 E(): 1.8e-05; 36.7% identity in 120 aa overlap. Contains possible N-terminal region signal peptide sequence. | 0.921 |
SCO1515 | SCO1944 | gene:17759101 | gene:17759541 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | 0.938 |
SCO1515 | SCO2851 | gene:17759101 | gene:17760462 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative membrane protein; SCE20.25c, possible membrane protein, len: 237 aa. Similar in parts to many bacterial inner membrane proteins e.g. Streptomyces coelicolor TR:O54569(EMBL:Y16311) inner membrane protein, STH24.05 (431 aa), fasta scores opt: 240 z-score: 285.1 E(): 1.7e-08 25.0% identity in 232 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | 0.878 |
SCO1515 | SCO3005 | gene:17759101 | gene:17760617 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.852 |
SCO1515 | SCO3883 | gene:17759101 | gene:17761510 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). | 0.883 |
SCO1515 | SCO4646 | gene:17759101 | gene:17762295 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.949 |
SCO1515 | SCO4722 | gene:17759101 | gene:17762371 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.985 |
SCO1515 | SCO5580 | gene:17759101 | gene:17763238 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative prokaryotic docking protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.568 |
SCO1515 | SCO6160 | gene:17759101 | gene:17763819 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative SecDF protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.995 |
SCO1516 | SCO1515 | gene:17759102 | gene:17759101 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.999 |
SCO1516 | SCO1517 | gene:17759102 | gene:17759103 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | SCL2.07c, possible secreted protein, len: 169 aa; similar to SW:YP88_MYCLE (EMBL:AL023591) Mycobacterium leprae hypothetical protein MCLB1259.04, 114 aa; fasta scores: opt: 205 z-score: 231.1 E(): 1.8e-05; 36.7% identity in 120 aa overlap. Contains possible N-terminal region signal peptide sequence. | 0.962 |
SCO1516 | SCO1944 | gene:17759102 | gene:17759541 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation (By similarity); Belongs to the SecG family. | 0.996 |
SCO1516 | SCO2851 | gene:17759102 | gene:17760462 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative membrane protein; SCE20.25c, possible membrane protein, len: 237 aa. Similar in parts to many bacterial inner membrane proteins e.g. Streptomyces coelicolor TR:O54569(EMBL:Y16311) inner membrane protein, STH24.05 (431 aa), fasta scores opt: 240 z-score: 285.1 E(): 1.7e-08 25.0% identity in 232 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | 0.903 |
SCO1516 | SCO3005 | gene:17759102 | gene:17760617 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.987 |
SCO1516 | SCO3883 | gene:17759102 | gene:17761510 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity). | 0.948 |
SCO1516 | SCO4646 | gene:17759102 | gene:17762295 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.997 |
SCO1516 | SCO4722 | gene:17759102 | gene:17762371 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.997 |
SCO1516 | SCO5580 | gene:17759102 | gene:17763238 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative prokaryotic docking protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.833 |
SCO1516 | SCO6160 | gene:17759102 | gene:17763819 | Protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | Putative SecDF protein-export membrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.994 |