STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO6597SC8A6.18, probable beta-glucosidase, len: 859 aa; si milar to many e.g. BGLS_AGRTU beta-glucosidase (EC 3.2.1.21) (818 aa), fasta scores; opt: 810 z-score: 1139.9 E(): 0, 37.2% identity in 862 aa overlap. (859 aa)    
Predicted Functional Partners:
SCO0458
SCF51A.36, probable Beta-glucosidase (EC 3.2.1.21), len: 762 aa. Highly similar to many e.g. Escherichia coli SW:BGLX_ECOLI (EMBL; U15049) periplasmic Beta-glucosidase precursor (EC 3.2.1.21) (765 aa), fasta scores opt: 851 z-score: 896.9 E(): 0 32.2% identity in 773 aa overlap. Contains 2x Pfam matches to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3.
  
  
 
0.928
SCO5685
SC5H4.09c, probable sugar hydrolase, len: 960 aa; similar to TR:Q59506 (EMBL:L06134) Microbispora bispora glucan-glucohydrolase (EC 3.2.1.74) (glucan 1,4-beta-glucosidase) (exo-1,4-beta-glucosidase) BglA, 986 aa; fasta scores: opt: 1257 z-score: 1346.1 E(): 0; 47.7% identity in 979 aa overlap. Contains Pfam matches to entries PF00933 Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain and PF01915 Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.
  
  
 
0.927
SCO1059
SCG22.05, probable beta-glucosidase, len: 459 aa; similar to TR:Q59976 (EMBL:Z29625) Streptomyces sp. beta-glucosidase (EC 3.2.1.21) Bgl3, 479 aa; fasta scores: opt: 1627 z-score: 1895.8 E(): 0; 57.6% identity in 458 aa overlap. Contains Pfam match to entry PF00232 Glyco_hydro_1, Glycosyl hydrolase family 1 and match to Prosite entry PS00653 Glycosyl hydrolases family 1 N-terminal signature.
    
 0.906
SCO2531
Putative beta-glucosidase; SCC117.04, possible beta-glucosidase, len: 448 aa. Highly similar to many including: Microbispora bispora SW:BGLB_MICBI(EMBL:M97265) thermostable beta-glucosidase B (EC 3.2.1.21) (473 aa), fasta scores opt: 1059 z-score: 1221.1 E(): 0 48.7% identity in 454 aa overlap and Paenibacillus polymyxa (Bacillus polymyxa) SW:BGLA_PAEPO(EMBL:M60210) beta-glucosidase A (EC 3.2.1.21) (448 aa), fasta scores opt: 1014 z-score: 1169.7 E():0 40.4% identity in 455 aa overlap. Contains a Prosite hit to PS00653 Glycosyl hydrolases family 1 N-terminal signature and a Pfam match [...]
    
 0.906
SCO2798
2SCC13.06, probable cellobiose hydrolase, len: 479 aa; highly similar to TR:Q59976 (EMBL:Z29625) Streptomyces sp. beta-glucosidase (EC 3.2.1.21) (cellobiose) Bgl3, 479 aa; fasta scores: opt: 2214 z-score: 2511.6 E(): 0; 65.5% identity in 472 aa overlap. Contains Pfam match to entry PF00232 Glyco_hydro_1, Glycosyl hydrolase family 1 and matches to Prosite entries PS00653 Glycosyl hydrolases family 1 N-terminal signature and PS00572 Glycosyl hydrolases family 1 active site.
    
 0.906
SCO6604
SC1F2.01, probable beta-glucosidase, partial CDS, len >311 aa; similar to mnay e.g. BGLS_AGRSP beta-glucosidase (EC 3.2.1.21) (459 aa), fasta scores; opt: 784 z-score: 986.7 E(): 0, 42.5% identity in 315 aa overlap. Overlaps and extends SC8A6.25. Contains Pfam match to entry PF00232 glycosyl_hydro1, Glycosyl hydrolases family 1, score 350.20, E-value 2.2e-101; SC8A6.25, probable beta-glucosidase, partial CDS, le n >190 aa; highly similar to many e.g. BGLA_BACCI beta-glucosidase (EC 3.2.1.21) (449 aa), fasta scores; opt: 752 z-sc ore: 1084.7 E(): 0, 59.9% identity in 167 aa overlap. Con [...]
    
 0.906
SCO7558
SC5F1.12, probable beta-glucosidase, len: 479 aa; similar to TR:Q59976 (EMBL:Z29625) Streptomyces sp. beta-glucosidase (EC 3.2.1.21) Bgl3, 479 aa; fasta scores: opt: 2961 z-score: 3301.3 E(): 0; 88.9% identity in 479 aa overlap and to TR:CAC10107 (EMBL:AL442165) Streptomyces coelicolor putative cellobiose hydrolase 2SCC13.06, 479 aa; fasta scores: opt: 2255 z-score: 2227.1 E(): 0; 67.4% identity in 470 aa overlap. Contains Pfam match to entry PF00232 Glyco_hydro_1, Glycosyl hydrolase family 1 and match to Prosite entry PS00653 Glycosyl hydrolases family 1 N-terminal signature and PS005 [...]
    
 0.906
SCO2661
SC6D10.04, possible sugar hydrolase, len: 421 aa; similar to SW:CELF_ECOLI (EMBL:X52890) Escherichia coli 6-phospho-beta-glucosidase (EC 3.2.1.86) CelF, 450 aa; fasta scores: opt: 556 z-score: 624.0 E(): 2.4e-27; 36.0% identity in 431 aa overlap and to SW:AGAL_ECOLI (EMBL:X04894) Escherichia coli alpha-galactosidase (EC 3.2.1.22) (melibiase) MelA, 451 aa; fasta scores: opt: 300 z-score: 338.4 E(): 1.9e-11; 25.5% identity in 459 aa overlap.
     
  0.900
SCO6548
SC5C7.33, probable secreted cellulase, len: 579 aa; similar to many, e.g. TR:Q60029 (EMBL:U18978) beta-1,4-exocellulase precursor (596 aa), fasta scores; opt: 2131 z-score: 2323.9 E(): 0, 62.1% identity in 585 aa overlap. Contains possible N-terminal signal sequence, PS00655 Glycosyl hydrolases family 6 signature 1 and Pfam match to entry PF00553 CBD_1, Cellulose binding domain, score 161.20, E-value 9.8e-46 near C-terminus.
 
   
 0.900
SCO6670
SC5A7.20, probable glucosidase, len: 441 aa; similar to e.g. CELF_ECOLI 6-phospho-beta-glucosidase (450 aa), fasta scores; opt: 537 z-score: 628.7 E(): 8.8e-28, 31.8% identity in 456 aa overlap.
     
  0.900
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: high (82%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.