node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO0717 | SCO0871 | gene:17758300 | gene:17758454 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | 0.401 |
SCO0717 | SCO2817 | gene:17758300 | gene:17760425 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | SCBAC17F8.08c, conserved hypothetical protein, len: 634 aa: similar in regions to many proteins of varying lengths e.g. TR:Q9RCY2 (EMBL:AL133469) hypothetical protein SCM10.16c from Streptomyces coelicolor (714 aa) fasta scores; opt: 1259, Z-score: 1358.4, 43.960% identity (46.454% ungapped) in 596 aa overlap and TR:Q9HVI8 (EMBL:AE004874) hypothetical protein from Pseudomonas aeruginosa (1415 aa) fasta scores; opt: 961, Z-score: 1032.5, 36.825% identity (40.250% ungapped) in 611 aa overlap. Contains Pfam match to entry PF00563 EAL, Domain of unknown function and Pfam match to entry PF0 [...] | 0.469 |
SCO0717 | SCO3067 | gene:17758300 | gene:17760682 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | SCE25.08c, putative anti anti sigma factor, len: 125 aa; identical to previously sequenced TR:CAB55835 (EMBL:AJ249581) Streptomyces coelicolor A3(2) putative anti anti sigma factor, 125 aa. Contains Pfam match to entry PF01740 SpoIIAA, SpoIIAA family; Belongs to the anti-sigma-factor antagonist family. | 0.616 |
SCO0717 | SCO3549 | gene:17758300 | gene:17761171 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | Putative anti-sigma factor antagonist; Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity). | 0.770 |
SCO0717 | SCO4410 | gene:17758300 | gene:17762055 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | SC6F11.08, possible anti anti sigma factor, len: 126 aa; similar to SW:RSBV_STRCO (EMBL:AF134889) Streptomyces coelicolor anti-sigma B factor antagonist BldG, 113 aa; fasta scores: opt: 195 z-score: 264.4 E(): 3.2e-07; 30.8% identity in 104 aa overlap. Contains Pfam match to entry PF01740 STAS, STAS domain; Belongs to the anti-sigma-factor antagonist family. | 0.456 |
SCO0717 | SCO5747 | gene:17758300 | gene:17763407 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | SC7C7.02c, possible regulatory protein, len: 916 aa; N-terminus is similar to S. coloicolor TR:Q53897 (EMBL:X60316) AbaA ORFA (192 aa), fasta scores; opt: 248 z-score: 257.6 E(): 4.1e-07, 34.2% identity in 187 aa overlapC-terminus is similar to several RsbU homologs e.g. Bacillus licheniformis TR:O50229 (EMBL:AF034567) putative sigma B regulator similar to B. subtilis RsbU phosphatase (335 aa), fasta scores; opt: 232 z-score: 196.5 E(): 0.001, 26.3% identity in 240 aa overlap. | 0.532 |
SCO0717 | SCO7009 | gene:17758300 | gene:17764669 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | Conserved hypothetical protein; SC8F11.35c, unknown, len: 593 aa. Identical, apart from the very C-terminus, to Streptomyces lividans TR:O86875(EMBL:U22894) hypothetical 57.9 kd protein, AglX (547 aa), fasta scores opt: 3357 z-score: 3741.0 E(): 0 98.8% identity in 519 aa overlap. Also highly similar to several Streptomyces coelicolor hypothetical proteins e.g. TR:CAB61537(EMBL:AL133171) SCF81.26 (835 aa), fasta scores opt: 1133 z-score: 1260.6 E(): 0 43.0% identity in 575 aa overlap. | 0.825 |
SCO0717 | SCO7573 | gene:17758300 | gene:17765233 | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | SC5F1.27c, probable anti-sigma factor antagonist, len: 114 aa; similar to SW:RSBV_STRCO (EMBL:AF134889) Streptomyces coelicolor anti-sigma factor B antagonist BldG, 113 aa; fasta scores: opt: 320 z-score: 436.5 E(): 8.8e-17; 49.5% identity in 99 aa overlap. Contains Pfam match to entry PF01740 STAS, STAS domain; Belongs to the anti-sigma-factor antagonist family. | 0.686 |
SCO0871 | SCO0717 | gene:17758454 | gene:17758300 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | 0.401 |
SCO0871 | SCO2817 | gene:17758454 | gene:17760425 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SCBAC17F8.08c, conserved hypothetical protein, len: 634 aa: similar in regions to many proteins of varying lengths e.g. TR:Q9RCY2 (EMBL:AL133469) hypothetical protein SCM10.16c from Streptomyces coelicolor (714 aa) fasta scores; opt: 1259, Z-score: 1358.4, 43.960% identity (46.454% ungapped) in 596 aa overlap and TR:Q9HVI8 (EMBL:AE004874) hypothetical protein from Pseudomonas aeruginosa (1415 aa) fasta scores; opt: 961, Z-score: 1032.5, 36.825% identity (40.250% ungapped) in 611 aa overlap. Contains Pfam match to entry PF00563 EAL, Domain of unknown function and Pfam match to entry PF0 [...] | 0.754 |
SCO0871 | SCO3067 | gene:17758454 | gene:17760682 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SCE25.08c, putative anti anti sigma factor, len: 125 aa; identical to previously sequenced TR:CAB55835 (EMBL:AJ249581) Streptomyces coelicolor A3(2) putative anti anti sigma factor, 125 aa. Contains Pfam match to entry PF01740 SpoIIAA, SpoIIAA family; Belongs to the anti-sigma-factor antagonist family. | 0.484 |
SCO0871 | SCO3549 | gene:17758454 | gene:17761171 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | Putative anti-sigma factor antagonist; Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity). | 0.484 |
SCO0871 | SCO4410 | gene:17758454 | gene:17762055 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SC6F11.08, possible anti anti sigma factor, len: 126 aa; similar to SW:RSBV_STRCO (EMBL:AF134889) Streptomyces coelicolor anti-sigma B factor antagonist BldG, 113 aa; fasta scores: opt: 195 z-score: 264.4 E(): 3.2e-07; 30.8% identity in 104 aa overlap. Contains Pfam match to entry PF01740 STAS, STAS domain; Belongs to the anti-sigma-factor antagonist family. | 0.484 |
SCO0871 | SCO5747 | gene:17758454 | gene:17763407 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SC7C7.02c, possible regulatory protein, len: 916 aa; N-terminus is similar to S. coloicolor TR:Q53897 (EMBL:X60316) AbaA ORFA (192 aa), fasta scores; opt: 248 z-score: 257.6 E(): 4.1e-07, 34.2% identity in 187 aa overlapC-terminus is similar to several RsbU homologs e.g. Bacillus licheniformis TR:O50229 (EMBL:AF034567) putative sigma B regulator similar to B. subtilis RsbU phosphatase (335 aa), fasta scores; opt: 232 z-score: 196.5 E(): 0.001, 26.3% identity in 240 aa overlap. | 0.855 |
SCO0871 | SCO5748 | gene:17758454 | gene:17763408 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SC7C7.03, probable sensory histidine kinase, len: 1829 aa; N-terminus has 11 92aa repeats. Highly similar to putative osmosensing histidine kinases from yeasts (with only five repeats) e.g. Neurospora crassa TR:Q01318 (EMBL:U53189) osmotic-1 locus putative histidine kinase (1298 aa), fasta scores; opt: 2011 z-score: 1764.6 E(): 0, 38.3% identity in 1281 aa overlap. Also similar to BARA_ECOLI sensor protein BarA (918 aa) (with only one copy of the repeat), fasta scores; opt: 378 z-score: 755.8, E(): 0, 28.9% identity in 619 aa overlap. Extreme N-terminus has similarity to the phosphoryl [...] | 0.986 |
SCO0871 | SCO7009 | gene:17758454 | gene:17764669 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | Conserved hypothetical protein; SC8F11.35c, unknown, len: 593 aa. Identical, apart from the very C-terminus, to Streptomyces lividans TR:O86875(EMBL:U22894) hypothetical 57.9 kd protein, AglX (547 aa), fasta scores opt: 3357 z-score: 3741.0 E(): 0 98.8% identity in 519 aa overlap. Also highly similar to several Streptomyces coelicolor hypothetical proteins e.g. TR:CAB61537(EMBL:AL133171) SCF81.26 (835 aa), fasta scores opt: 1133 z-score: 1260.6 E(): 0 43.0% identity in 575 aa overlap. | 0.847 |
SCO0871 | SCO7327 | gene:17758454 | gene:17764987 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SC4G10.06c, possible two-component system sensory histidine kinase, len: 1331 aa. Highly similar in parts to many including: Pseudomonas syringae (pv. syringae) SW:LEMA_PSESY(EMBL:M80477) sensor protein, LemA (EC 2.7.3.-), (907 aa), fasta scores opt: 641 z-score: 627.6 E(): 1.7e-27 31.2% identity in 872 aa overlap and Streptomyces coelicolor TR:O86808(EMBL:AL031031) putative sensory histidine kinase, SC7C7.03 (1829 aa), fasta scores opt: 2600 z-score: 2540.8 E():0 59.1% identity in 1346 aa overlap. Contains Pfam matches to entries PF00072 response_reg, Response regulator receiver domai [...] | 0.986 |
SCO0871 | SCO7573 | gene:17758454 | gene:17765233 | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | SC5F1.27c, probable anti-sigma factor antagonist, len: 114 aa; similar to SW:RSBV_STRCO (EMBL:AF134889) Streptomyces coelicolor anti-sigma factor B antagonist BldG, 113 aa; fasta scores: opt: 320 z-score: 436.5 E(): 8.8e-17; 49.5% identity in 99 aa overlap. Contains Pfam match to entry PF01740 STAS, STAS domain; Belongs to the anti-sigma-factor antagonist family. | 0.550 |
SCO2817 | SCO0717 | gene:17760425 | gene:17758300 | SCBAC17F8.08c, conserved hypothetical protein, len: 634 aa: similar in regions to many proteins of varying lengths e.g. TR:Q9RCY2 (EMBL:AL133469) hypothetical protein SCM10.16c from Streptomyces coelicolor (714 aa) fasta scores; opt: 1259, Z-score: 1358.4, 43.960% identity (46.454% ungapped) in 596 aa overlap and TR:Q9HVI8 (EMBL:AE004874) hypothetical protein from Pseudomonas aeruginosa (1415 aa) fasta scores; opt: 961, Z-score: 1032.5, 36.825% identity (40.250% ungapped) in 611 aa overlap. Contains Pfam match to entry PF00563 EAL, Domain of unknown function and Pfam match to entry PF0 [...] | SCF42.27, possible integral membrane protein, len: 375 aa. Similar to several other membrane proteins from Streptomyces coelicolor e.g. TR:CAB56388(EMBL:AL118515) SCD17.11 (454 aa), fasta scores opt: 569 z-score: 648.9 E(): 9.3e-29 36.4% identity in 360 aa overlap. Contains multiple possible membrane spanning hydrophobic domains. | 0.469 |
SCO2817 | SCO0871 | gene:17760425 | gene:17758454 | SCBAC17F8.08c, conserved hypothetical protein, len: 634 aa: similar in regions to many proteins of varying lengths e.g. TR:Q9RCY2 (EMBL:AL133469) hypothetical protein SCM10.16c from Streptomyces coelicolor (714 aa) fasta scores; opt: 1259, Z-score: 1358.4, 43.960% identity (46.454% ungapped) in 596 aa overlap and TR:Q9HVI8 (EMBL:AE004874) hypothetical protein from Pseudomonas aeruginosa (1415 aa) fasta scores; opt: 961, Z-score: 1032.5, 36.825% identity (40.250% ungapped) in 611 aa overlap. Contains Pfam match to entry PF00563 EAL, Domain of unknown function and Pfam match to entry PF0 [...] | SCM1.04c, possible two-component sensor protein. Len: 545 aa. Similar, in parts, to many others including: Methanobacterium thermoautotrophicum TR:O26544(EMBL:AE000828) signal-transducing histidine kinase (373 aa), fasta scores opt: 509 z-score: 548.0 E(): 3.5e-23 34.2% identity in 313 aa overlap and Streptomyces coelicolor TR:O88056(EMBL:AL031541) putative two-component sensor (379 aa), fasta scores opt:350 z-score: 378.5 E(): 9.7e-14 35.6% identity in 233 aa overlap. Contains a Pfam matches to entries PF00512 signal, Histidine kinase and Pfam match to entry PF00672 DUF5, Domain found [...] | 0.754 |