STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO7044Putative integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (154 aa)    
Predicted Functional Partners:
SCO7046
Putative integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
 
  
 0.987
SCO7045
SC4G1.11, hypothetical protein, len: 114 aa; similar to TR:O59172 (EMBL:AP000006) Pyrococcus horikoshii hypothetical 14.9 kDa protein PH1503, 130 aa; fasta scores: opt: 302 z-score: 405.0 E(): 4.3e-15; 41.0% identity in 100 aa overlap; Belongs to the UPF0166 family.
 
   
 0.943
SCO7043
Hypothetical protein SC4G1.09; SC4G1.09, unknown, len: 110 aa. Highly hydrophilic.
  
  
 0.754
SCO7047
Putative transport integral membrane protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
       0.704
SCO4185
SCD66.22, conserved hypothetical protein, len: 336 aa; highly similar to TR:Q54237 (EMBL:D63706) Streptomyces griseus ORF4 hypothetical protein, 328 aa; fasta scores: opt: 1654 z-score: 1801.0 E(): 0; 78.6% identity in 322 aa overlap and N-terminal domain identical to TR:Q9Z4H1 (EMBL:D63677) Streptomyces coelicolor ORF4 hypothetical protein (fragment), 142 aa. Contains 3x degenerate repeat at N-terminal domain: PS(H/Q).
 
     0.611
SCO4094
Conserved hypothetical protein SCD25.30; SCD25.30, unknown, len: 116 aa. Highly similar to Mycobacterium tuberculosis TR:P96242 (EMBL; Z83864) hypothetical 15.0 KD protein (137 aa), fasta scores opt: 395 z-score: 500.7 E(): 1.5e-20 54.4% identity in 114 aa overlap. Contains a Prosite hit to PS00142 Neutral zinc metallopeptidases, zinc-binding region signature.
       0.560
SCO6195
SC2G5.16, probable acetyl-coenzyme A synthetase, len:558 aa; similar to many e.g. SW:ACSA_BACSU from Bacillus subtilis (572 aa) fasta scores; opt: 798, z-score: 878.3,E():0, (31.8% identity in 537 aa overlap). Contains Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31. Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme, score 116.90, E-value 3.8e-31.
      
 0.410
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.