STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO7257Putative secreted protein; SC5H1.35c, possible hypothetical protein, len: 237 aa; unknown function, probable CDS suggested by positional base preference, GC frame analysis, amino acid composition and the presence of a possible RBS. Similar to TR:Q9AD93 (EMBL:AL590507) Streptomyces coelicolor hypothetical protein SCI52.16c, 259 aa; fasta scores: opt: 566 Z-score: 492.9 E(): 8e-20; 46.154% identity in 260 aa overlap. Contains possible N-terminal peptide signal sequence (237 aa)    
Predicted Functional Partners:
SCO4430
Putative secreted protein; SCD6.08, possible hypothetical protein, len: 189 aa; similar to TR:O86790 (EMBL:AL031317) Streptomyces coelicolor hypothetical protein SC6G4.27c, 184 aa; fasta scores: opt: 495 z-score: 536.2 E(): 2.1e-22; 48.1% identity in 181 aa overlap. Contains possible N-terminal region signal peptide sequence
  
     0.573
SCO5474
Uncharacterized protein; SC2A11.08, unknown, len: 255 aa
  
     0.530
SCO7255
SC5H1.37, hypothetical protein, len: 364 aa; unknown function, similar to TR:P73120 (EMBL:D90903) Synechocystis sp. hypothetical protein (358 aa), fasta scores; opt: 492 z-score: 559.6 E(): 7.6e-24, 31.6% identity in 364 aa overlap
 
     0.526
SCO1756
Uncharacterized protein; 2SCI34.09, unknown, len: 265 aa
  
     0.520
SCO4239
SCD8A.12c, possible small membrane protein, len: 148 aa; similar to TR:P96484 (EMBL:Y08921) Streptomyces reticuli hypothetical 15.9 kD protein, MsiK, 152 aa; fasta scores: opt: 724 z-score: 885.9 E(): 0; 74.8% identity in 151 aa overlap. Contains possible hydrophobic membrane spanning region
  
     0.515
SCO2820
SCBAC17F8.11c, hypothetical protein, len: 115 aa: no significant database matches
  
     0.514
SCO2279
Uncharacterized protein; SCC75A.25c, unknown, len: 243 aa
  
     0.509
SCO4237
SCD8A.10, possible integral membrane protein, len: 571 aa. Contains possible hydrophobic membrane spanning regions
  
     0.507
SCO1195
SCG11A.26c, membrane protein, len: 64 aa. Contains possible hydrophobic membrane spanning regions
  
     0.497
SCO1757
Uncharacterized protein; 2SCI34.10, unknown, len: 97 aa
  
     0.490
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor, Streptomyces coelicolor A3(2)
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