node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCO4701 | SCO5822 | gene:17762350 | gene:17763482 | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id entity in 683 aa overlap. Contains PS00177 DNA topoisomeras e II signature and Pfam match to entry DNA_topoisoII PF0020 4, DNA topoisomerase II, score 609.86. | 0.530 |
SCO4701 | SCO7700 | gene:17762350 | gene:17765360 | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | Putative cyclase; Catalyzes the cyclization of 2-methylgeranyl diphosphate (2- MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%). Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily. | 0.841 |
SCO5222 | SCO6073 | gene:17762873 | gene:17763732 | Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | 0.945 |
SCO5222 | SCO6750 | gene:17762873 | gene:17764408 | Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. | Putative IPP isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.732 |
SCO5222 | SCO7700 | gene:17762873 | gene:17765360 | Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. | Putative cyclase; Catalyzes the cyclization of 2-methylgeranyl diphosphate (2- MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%). Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily. | 0.695 |
SCO5222 | SCO7701 | gene:17762873 | gene:17765361 | Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. | Putative methyltransferase; Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP). | 0.668 |
SCO5822 | SCO4701 | gene:17763482 | gene:17762350 | SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id entity in 683 aa overlap. Contains PS00177 DNA topoisomeras e II signature and Pfam match to entry DNA_topoisoII PF0020 4, DNA topoisomerase II, score 609.86. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.530 |
SCO5822 | SCO6442 | gene:17763482 | gene:17764099 | SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id entity in 683 aa overlap. Contains PS00177 DNA topoisomeras e II signature and Pfam match to entry DNA_topoisoII PF0020 4, DNA topoisomerase II, score 609.86. | SC9B5.09, probable alcohol dehydrogenase, len: 367aa; similar to many eg. SW:XYLB_PSEPU aryl-alcohol dehydrogenase from Pseudomonas putida (366 aa) fasta scores; opt: 928, z-score: 888.5, E(): 0, (42.6% identity in 366 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | 0.565 |
SCO5822 | SCO6782 | gene:17763482 | gene:17764440 | SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id entity in 683 aa overlap. Contains PS00177 DNA topoisomeras e II signature and Pfam match to entry DNA_topoisoII PF0020 4, DNA topoisomerase II, score 609.86. | SC6A5.31c, probable zinc-binding alcohol dehydrogenase, len: 363aa; similar to many eg. TR:Q59096 (EMBL:U61983) benzyl alcohol dehydrogenase from Acinetobacter calcoaceticus (371 aa) fasta scores; opt: 948, z-score: 937.8, E(): 0, (42.8% identity in 360 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature. | 0.565 |
SCO5822 | SCO7700 | gene:17763482 | gene:17765360 | SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id entity in 683 aa overlap. Contains PS00177 DNA topoisomeras e II signature and Pfam match to entry DNA_topoisoII PF0020 4, DNA topoisomerase II, score 609.86. | Putative cyclase; Catalyzes the cyclization of 2-methylgeranyl diphosphate (2- MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%). Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily. | 0.682 |
SCO6073 | SCO5222 | gene:17763732 | gene:17762873 | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. | 0.945 |
SCO6073 | SCO6750 | gene:17763732 | gene:17764408 | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | Putative IPP isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.503 |
SCO6073 | SCO7699 | gene:17763732 | gene:17765359 | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | SC1A4.07, possible nucleotide-binding protein, len: 471 aa; highly similar to TR:Q54255 (EMBL:L76204) Streptomyces griseus sporulation-specific protein p3, 470 aa; fasta scores: opt: 2382 z-score: 2757.2 E(): 0; 75.8% identity in 472 aa overlap and to TR:CAC05970 (EMBL:AL391763) Streptomyces coelicolor putative nucleotide binding protein 2SC7G11.11, 468 aa; fasta scores: opt: 1972 z-score: 2283.0 E(): 0; 63.5% identity in 466 aa overlap. Contains Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain. | 0.813 |
SCO6073 | SCO7700 | gene:17763732 | gene:17765360 | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | Putative cyclase; Catalyzes the cyclization of 2-methylgeranyl diphosphate (2- MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%). Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily. | 0.888 |
SCO6073 | SCO7701 | gene:17763732 | gene:17765361 | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | Putative methyltransferase; Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP). | 0.795 |
SCO6442 | SCO5822 | gene:17764099 | gene:17763482 | SC9B5.09, probable alcohol dehydrogenase, len: 367aa; similar to many eg. SW:XYLB_PSEPU aryl-alcohol dehydrogenase from Pseudomonas putida (366 aa) fasta scores; opt: 928, z-score: 888.5, E(): 0, (42.6% identity in 366 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | SC5B8.12, gyrB2, probable DNA gyrase subunit B, len: 707 aa; highly similar to many e.g. GYRB_STAAU P20832 staph ylococcus aureus. dna gyrase subunit B (EC 5.99.1.3) (643 a a), fasta scores; opt: 954 z-score: 2020.9 E(): 0, 45.2% id entity in 683 aa overlap. Contains PS00177 DNA topoisomeras e II signature and Pfam match to entry DNA_topoisoII PF0020 4, DNA topoisomerase II, score 609.86. | 0.565 |
SCO6442 | SCO6782 | gene:17764099 | gene:17764440 | SC9B5.09, probable alcohol dehydrogenase, len: 367aa; similar to many eg. SW:XYLB_PSEPU aryl-alcohol dehydrogenase from Pseudomonas putida (366 aa) fasta scores; opt: 928, z-score: 888.5, E(): 0, (42.6% identity in 366 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | SC6A5.31c, probable zinc-binding alcohol dehydrogenase, len: 363aa; similar to many eg. TR:Q59096 (EMBL:U61983) benzyl alcohol dehydrogenase from Acinetobacter calcoaceticus (371 aa) fasta scores; opt: 948, z-score: 937.8, E(): 0, (42.8% identity in 360 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases and Prosite match to PS00059 Zinc-containing alcohol dehydrogenases signature. | 0.913 |
SCO6442 | SCO7700 | gene:17764099 | gene:17765360 | SC9B5.09, probable alcohol dehydrogenase, len: 367aa; similar to many eg. SW:XYLB_PSEPU aryl-alcohol dehydrogenase from Pseudomonas putida (366 aa) fasta scores; opt: 928, z-score: 888.5, E(): 0, (42.6% identity in 366 aa overlap). Contains Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenases. | Putative cyclase; Catalyzes the cyclization of 2-methylgeranyl diphosphate (2- MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate. Is also able to catalyze the cyclization of geranyl diphosphate (GPP), albeit with much lower efficiency, leading to the formation of a complex mixture of cyclic monoterpenes, consisting of alpha-pinene (6%), beta-pinene (23%), limonene (32%), gamma-terpinene (29%), and delta-terpinene (10%). Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily. | 0.689 |
SCO6750 | SCO5222 | gene:17764408 | gene:17762873 | Putative IPP isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | Putative lyase; Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene. | 0.732 |
SCO6750 | SCO6073 | gene:17764408 | gene:17763732 | Putative IPP isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | Putative cyclase; Tow-domain protein where the N-terminal domain catalyzes the cyclization of farnesyl diphosphate (FPP) to a 85:15 mixture of the sesquiterpene alcohol germacradienol and the sesquiterpene hydrocarbon germacrene D. The C-terminal domain partially converts the germacradienol formed into geosmin, the characteristic odoriferous ('earthy aroma') constituent of Streptomyces species. | 0.503 |