STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCO7747SC8D11.38, hypothetical protein, len: 392 aa; similar to TR:Q9L195 (EMBL:AL158057) Streptomyces coelicolor hypothetical 47.1 kDa protein SC10G8.07c, 437 aa; fasta scores: opt: 419 z-score: 494.1 E(): 5.5e-20; 28.5% identity in 393 aa overlap. (392 aa)    
Predicted Functional Partners:
SCO2560
Conserved hypothetical protein; SCC77.27c, unknown, len: 792 aa. Weakly similar to Streptomyces coelicolor TR:O86807 (EMBL:AL031031) putative regulatory protein SC7C7.02C (916 aa), fasta scores opt: 447 z-score: 376.3 E(): 1.4e-13 34.1% identity in 954 aa overlap. The N-terminus is also similar Streptomyces coelicolor TR:Q53897(EMBL:X60316) OrfA within the AbaA pleiotropic regulatory locus for antibiotic production (192 aa), fasta scores opt: 248 z-score: 220.6 E(): 6.7e-05 37.1% identity in 178 aa overlap.
 
   0.750
SCO3796
SCAC2.04, hypothetical protein, len: 722 aa; similar to TR:Q9RIW0 (EMBL:AL133278) Streptomyces coelicolor hypothetical 64.1 kDa protein (fragment) SCM11.01c, 588 aa; fasta scores: opt: 1053 z-score: 1177.1 E(): 0; 35.8% identity in 598 aa overlap.
 
   0.740
SCO0751
SCF81.10c, possible regulatory protein, len: 894 aa; similar to TR:Q9ZBJ0 (EMBL:AL035161) Streptomyces coelicolor conserved hypothetical protein SC9C7.20, 860 aa; fasta scores: opt: 663 z-score: 716.6 E(): 1.5e-32; 29.6% identity in 873 aa overlap and to TR:CAB44394 (EMBL:AL078610) Streptomyces coelicolor putative regulatory protein SCH35.33c, 422 aa; fasta scores: opt: 305 z-score: 312.4 E(): 5e-10; 33.3% identity in 258 aa overlap. Contains match to Pfam entry PF01590 GAF, GAF domain.
  
   0.737
SCO3284
SCE15.01, partial CDS, conserved hypothetical protein, len: >436aa; similar to C-terminal region of TR:CAA22732 (EMBL:AL035161) another conserved hypothetical protein from Streptomyces coelicolor (860 aa) fasta scores; opt: 922, z-score: 1011.5, E(): 0, (39.5% identity in 425 aa overlap); SCE39.34, unknown, len: >307aa; similar to TR:E1370406 (EMBL:AL035161) conserved hypothetical protein from Streptomyces coelicolor (860 aa) fasta scores; opt: 254, z-score: 277.0, E(): 4e-08, (29.2% identity in 277 aa overlap) TR:O86875 (EMBL:U22894) hypothetical protein from Streptomyces lividans (54 [...]
 
 
 0.710
SCO7009
Conserved hypothetical protein; SC8F11.35c, unknown, len: 593 aa. Identical, apart from the very C-terminus, to Streptomyces lividans TR:O86875(EMBL:U22894) hypothetical 57.9 kd protein, AglX (547 aa), fasta scores opt: 3357 z-score: 3741.0 E(): 0 98.8% identity in 519 aa overlap. Also highly similar to several Streptomyces coelicolor hypothetical proteins e.g. TR:CAB61537(EMBL:AL133171) SCF81.26 (835 aa), fasta scores opt: 1133 z-score: 1260.6 E(): 0 43.0% identity in 575 aa overlap.
 
   0.685
SCO7748
SC8D11.39, hypothetical protein, len: 567 aa; similar to TR:CAC14487 (EMBL:AL446003) Streptomyces coelicolor putative DNA-binding protein SC5E9.07, 531 aa; fasta scores: opt: 473 z-score: 523.3 E(): 1.3e-21; 30.3% identity in 433 aa overlap. Contains match to Prosite entry PS00237 G-protein coupled receptors signature and 4x degenerate repeat: HAVVP.
 
     0.682
SCO7158
SC9A4.20, conserved hypothetical protein, len: 812 aa; similar to TR:Q9RJC6 (EMBL:AL133171) Streptomyces coelicolor hypothetical 89.7 kDa protein SCF81.26, 835 aa; fasta scores: opt: 1262 z-score: 1348.6 E(): 0; 37.3% identity in 808 aa overlap. Contains 2x Pfam matches to entry PF00989 PAS, PAS domain, Pfam match to PF00785 PAC, PAC motif and match to Prosite entry PS00213 Lipocalin signature.
 
  
 0.668
SCO0946
Putative regulatory protein; SCM11.01c, hypothetical protein, len: >587 aa; similar to various hypothetical proteins, e.g. TR:Q9ZBJ0 (EMBL:AL035161) Streptomyces coelicolor conserved hypothetical protein SC9C7.20, 860 aa; fasta scores: opt: 588 z-score: 654.5 E(): 4.4e-29; 30.4% identity in 542 aa overlap; SCM10.35c, possible regulatory protein, (partial CDS), len: >141 aa; similar to TR:Q9ZBT2 (EMBL:AL034446)Streptomyces coelicolor putative regulatory protein SC1A9.20, 135 aa; fasta scores: opt: 286 z-score: 366.0 E(): 5.3e-13; 42.4% identity in 132 aa overlap.
  
     0.655
SCO7320
Conserved hypothetical protein SC5F8.30c; SC5F8.30c, unknown, len: 580 aa. Similar in parts to many Streptomyces coelicolor proteins of undefined function including: TR:Q9RJE1(EMBL:AL133171) putative regulatory protein, SCF81.10C (828 aa), fasta scores opt: 676 z-score: 710.0 E(): 4.5e-32 34.7% identity in 426 aa overlap and TR:Q9X8W1(EMBL:AL078610;) hypothetical 66.2 kd protein, SCH35.45C (634 aa), fasta scores opt: 633 z-score: 666.6 E(): 1.2e-29 33.4% identity in 539 aa overlap.
 
     0.655
SCO7750
SC8D11.41, hypothetical protein, len: 137 aa; low similarity to TR:Q9RIS6 (EMBL:AJ249581) Streptomyces coelicolor putative anti anti sigma factor SCE25.08c, 125 aa; fasta scores: opt: 110 z-score: 148.5 E(): 0.98; 33.8% identity in 77 aa overlap.
  
   0.629
Your Current Organism:
Streptomyces coelicolor
NCBI taxonomy Id: 100226
Other names: S. coelicolor A3(2), Streptomyces coelicolor A3(2)
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