STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCB1ATP-dependent translocase ABCB1; Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D- glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily. (1276 aa)    
Predicted Functional Partners:
Abcc3
Canalicular multispecific organic anion transporter 2.
   
 0.785
Slc25a40
Solute carrier family 25 member 40-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.553
Abcc5
Multidrug resistance-associated protein 5.
   
0.520
Abcc4
Multidrug resistance-associated protein 4.
   
0.511
Katnal2
Katanin p60 ATPase-containing subunit A-like 2.
  
 0.496
I79_007383
Katanin p60 ATPase-containing subunit A-like 2.
  
 0.496
I79_024752
26S proteasome non-ATPase regulatory subunit 3.
   
 0.483
I79_024753
26S proteasome non-ATPase regulatory subunit 3.
   
 0.483
I79_026038
26S proteasome non-ATPase regulatory subunit 3.
   
 0.483
Nr1i2
Nuclear receptor subfamily 1 group I member 2.
   
 0.474
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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