STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pea15Astrocytic phosphoprotein PEA-15. (130 aa)    
Predicted Functional Partners:
I79_009500
Mitogen-activated protein kinase 1.
    
 0.866
Mapk3
Mitogen-activated protein kinase.
    
 0.866
I79_001733
Mitogen-activated protein kinase.
    
 0.786
I79_017529
Apoptotic protease-activating factor 1.
    
 0.745
I79_017669
Apoptotic protease-activating factor 1.
    
 0.745
Appl1
DCC-interacting protein 13-alpha.
    
 0.728
I79_016547
DCC-interacting protein 13-beta.
    
 0.728
Birc6
Baculoviral IAP repeat-containing protein 6.
   
 0.667
Fadd
FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
    
 0.663
Mapk13
Mitogen-activated protein kinase.
    
 0.611
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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