STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Axin1Axin-1. (863 aa)    
Predicted Functional Partners:
Gsk3b
Glycogen synthase kinase-3 beta.
   
 0.999
Ctnnb1
Catenin beta-1.
   
 0.998
Apc
Adenomatous polyposis coli protein.
   
 0.998
Dvl1
Putative segment polarity protein dishevelledVL-1-like protein.
   
 0.994
Apc2
Adenomatous polyposis coli protein 2.
   
 0.990
Dvl3
Segment polarity protein dishevelled-like DVL-3.
   
 0.989
Axin2
Axin-2.
    
0.986
Gsk3a
Glycogen synthase kinase-3 alpha.
   
 0.981
Tnks
Poly [ADP-ribose] polymerase.
    
 0.964
Phf23
Segment polarity protein dishevelled-like DVL-2.
   
0.959
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.