STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Shc1SHC-transforming protein 1. (579 aa)    
Predicted Functional Partners:
CgPICR_012052
Growth factor receptor-bound protein 2.
   
 0.997
Erbb2
Receptor protein-tyrosine kinase.
    
 0.995
Igf1r
Insulin-like growth factor 1 receptor.
    
 0.990
Sos2
Son of sevenless-like 2.
   
 0.989
Src
Tyrosine-protein kinase.
   
0.987
I79_008941
Receptor protein-tyrosine kinase.
    
 0.979
Fyn
Proto-oncogene tyrosine-protein kinase Fyn.
   
 0.979
Insr
Insulin receptor.
    
 0.978
I79_005331
Receptor tyrosine-protein kinase erbB-4.
    
 0.974
Jak2
Tyrosine-protein kinase.
   
 0.973
Your Current Organism:
Cricetulus griseus
NCBI taxonomy Id: 10029
Other names: C. griseus, CHO cell lines, Chinese hamster, Chinese hamsters, Cricetulus aureus, Cricetulus barabensis griseus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.