STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD36Platelet glycoprotein 4; Multifunctional glycoprotein that acts as receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor- ligand complexes. The depende [...] (472 aa)    
Predicted Functional Partners:
Thbs1
Thrombospondin-1 isoform X1; Thrombospondin-1
   
 0.986
Thbs2
Thrombospondin-2
    
 0.919
Thbs4
Thrombospondin-4
   
 0.880
Comp
Cartilage oligomeric matrix protein
   
 0.863
Thbs3
Thrombospondin-3 isoform X1
    
 0.861
Fyn
Tyrosine-protein kinase Fyn isoform X1
    
 0.831
ppara
Peroxisome proliferator-activated receptor alpha isoform x2; Peroxisome proliferator-activated receptor alpha
   
 
 0.784
APOAI
Truncated apolipoprotein a-i; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility
   
 0.757
Itga2b
Integrin alpha-iib isoform x1; Belongs to the integrin alpha chain family
    
 0.733
Gp5
Platelet glycoprotein V
     
 0.733
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Microcricetus aureus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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