STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rab5cRas-related protein Rab-5C (216 aa)    
Predicted Functional Partners:
Eea1
Early endosome antigen 1
   
 0.984
Pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family
   
 0.967
Rabgef1
rab5 GDP/GTP exchange factor isoform X1; Rab5 GDP/GTP exchange factor
   
 0.963
Rab5a
Ras-related protein Rab-5A isoform X1
  
0.957
Rabep1
Rab GTPase-binding effector protein 1 isoform X1
   
 0.931
Rbsn
LOW QUALITY PROTEIN: rabenosyn-5
   
 0.927
Rin1
Ras and Rab interactor 1
    
 0.918
Gdi2
Rab gdp dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP
   
 0.893
Gdi1
Rab gdp dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP
   
 0.893
Rin2
Ras and Rab interactor 2
   
 0.887
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Microcricetus aureus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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