STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (389 aa)    
Predicted Functional Partners:
MMYC01_200392
Pre-mRNA-processing factor 19.
    
   0.914
MMYC01_200233
Pre-mRNA-splicing factor syf1.
    
 
 0.735
MMYC01_205894
Pre-mRNA-splicing factor prp46.
    
   0.725
MMYC01_203577
Pre-mRNA-splicing factor cef-1.
    
   0.671
MMYC01_208349
G patch domain-containing protein 1.
    
   0.539
MMYC01_205415
Peptidyl-prolyl cis-trans isomerase E.
    
   0.536
MMYC01_202671
Squamous cell carcinoma antigen recognized by T-cells 3.
    
 
 0.535
MMYC01_203257
Pre-mRNA-splicing factor SPF27.
    
   0.530
MMYC01_204906
Pre-mRNA-splicing factor cwf19.
    
   0.528
LSM8
U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
      
 0.485
Your Current Organism:
Madurella mycetomatis
NCBI taxonomy Id: 100816
Other names: M. mycetomatis, Madurella ikedae, Madurella mycetomi, Streptotrix mycetomatis
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