node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dclre1b | Pcbp3 | ENSMUSP00000029435 | ENSMUSP00000001148 | 5' exonuclease Apollo; 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)- mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres [...] | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.427 |
Dclre1b | Zfp827 | ENSMUSP00000029435 | ENSMUSP00000096214 | 5' exonuclease Apollo; 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)- mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres [...] | Zinc finger protein 827; May be involved in transcriptional regulation. | 0.636 |
Dnajb4 | Pcbp3 | ENSMUSP00000053916 | ENSMUSP00000001148 | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.416 |
Pcbp3 | Dclre1b | ENSMUSP00000001148 | ENSMUSP00000029435 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 5' exonuclease Apollo; 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)- mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres [...] | 0.427 |
Pcbp3 | Dnajb4 | ENSMUSP00000001148 | ENSMUSP00000053916 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | DnaJ homolog subfamily B member 4; Probable chaperone. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). | 0.416 |
Pcbp3 | Pofut2 | ENSMUSP00000001148 | ENSMUSP00000020493 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13 (By similarity). O- fucosylation of TS [...] | 0.482 |
Pcbp3 | Prpf8 | ENSMUSP00000001148 | ENSMUSP00000018449 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | 0.485 |
Pcbp3 | Ptbp2 | ENSMUSP00000001148 | ENSMUSP00000029780 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. | 0.416 |
Pcbp3 | Rbm11 | ENSMUSP00000001148 | ENSMUSP00000109891 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Splicing regulator RBM11; Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1 (By similarity). | 0.588 |
Pcbp3 | Rgsl1 | ENSMUSP00000001148 | ENSMUSP00000135642 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Regulator of G-protein-signaling-like 1. | 0.519 |
Pcbp3 | Ybey | ENSMUSP00000001148 | ENSMUSP00000045647 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family. | 0.543 |
Pcbp3 | Zfp827 | ENSMUSP00000001148 | ENSMUSP00000096214 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Zinc finger protein 827; May be involved in transcriptional regulation. | 0.445 |
Pcbp3 | Zfp830 | ENSMUSP00000001148 | ENSMUSP00000056154 | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | Zinc finger protein 830; May play a role in pre-mRNA splicing as component of the spliceosome (By similarity). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During ear [...] | 0.422 |
Pofut2 | Pcbp3 | ENSMUSP00000020493 | ENSMUSP00000001148 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13 (By similarity). O- fucosylation of TS [...] | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.482 |
Pofut2 | Ybey | ENSMUSP00000020493 | ENSMUSP00000045647 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively. O-fucosylates members of several protein families including the ADAMTS superfamily and the thrombosporin (TSP) and spondin families. Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13 (By similarity). O- fucosylation of TS [...] | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family. | 0.701 |
Prpf8 | Pcbp3 | ENSMUSP00000018449 | ENSMUSP00000001148 | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.485 |
Prpf8 | Zfp830 | ENSMUSP00000018449 | ENSMUSP00000056154 | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | Zinc finger protein 830; May play a role in pre-mRNA splicing as component of the spliceosome (By similarity). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During ear [...] | 0.945 |
Ptbp2 | Pcbp3 | ENSMUSP00000029780 | ENSMUSP00000001148 | Polypyrimidine tract-binding protein 2; RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.416 |
Rbm11 | Pcbp3 | ENSMUSP00000109891 | ENSMUSP00000001148 | Splicing regulator RBM11; Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1 (By similarity). | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.588 |
Rgsl1 | Pcbp3 | ENSMUSP00000135642 | ENSMUSP00000001148 | Regulator of G-protein-signaling-like 1. | Poly(rC)-binding protein 3; Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. | 0.519 |