node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Brix1 | Ebna1bp2 | ENSMUSP00000022855 | ENSMUSP00000030501 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.999 |
Brix1 | Grwd1 | ENSMUSP00000022855 | ENSMUSP00000116252 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.931 |
Brix1 | Gtpbp4 | ENSMUSP00000022855 | ENSMUSP00000152412 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.997 |
Brix1 | Noc2l | ENSMUSP00000022855 | ENSMUSP00000137253 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.993 |
Brix1 | Pes1 | ENSMUSP00000022855 | ENSMUSP00000020705 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.989 |
Brix1 | Pwp1 | ENSMUSP00000022855 | ENSMUSP00000001836 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Periodic tryptophan protein 1 homolog; Chromatin-associated factor that regulates transcription (By similarity). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (By similarity). Regulates the epigenetic status of rDNA (By similarity). | 0.944 |
Brix1 | Rpf2 | ENSMUSP00000022855 | ENSMUSP00000138581 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.991 |
Brix1 | Rsl1d1 | ENSMUSP00000022855 | ENSMUSP00000113431 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.993 |
Brix1 | Sdad1 | ENSMUSP00000022855 | ENSMUSP00000031364 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm. | 0.814 |
Brix1 | Wdr3 | ENSMUSP00000022855 | ENSMUSP00000060613 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | WD repeat-containing protein 3. | 0.839 |
Ebna1bp2 | Brix1 | ENSMUSP00000030501 | ENSMUSP00000022855 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.999 |
Ebna1bp2 | Grwd1 | ENSMUSP00000030501 | ENSMUSP00000116252 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.874 |
Ebna1bp2 | Gtpbp4 | ENSMUSP00000030501 | ENSMUSP00000152412 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.993 |
Ebna1bp2 | Noc2l | ENSMUSP00000030501 | ENSMUSP00000137253 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.997 |
Ebna1bp2 | Pes1 | ENSMUSP00000030501 | ENSMUSP00000020705 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Ebna1bp2 | Pwp1 | ENSMUSP00000030501 | ENSMUSP00000001836 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Periodic tryptophan protein 1 homolog; Chromatin-associated factor that regulates transcription (By similarity). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (By similarity). Regulates the epigenetic status of rDNA (By similarity). | 0.965 |
Ebna1bp2 | Rpf2 | ENSMUSP00000030501 | ENSMUSP00000138581 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.996 |
Ebna1bp2 | Rsl1d1 | ENSMUSP00000030501 | ENSMUSP00000113431 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.995 |
Ebna1bp2 | Sdad1 | ENSMUSP00000030501 | ENSMUSP00000031364 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm. | 0.874 |
Ebna1bp2 | Wdr3 | ENSMUSP00000030501 | ENSMUSP00000060613 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | WD repeat-containing protein 3. | 0.793 |