node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Armc6 | Slc25a42 | ENSMUSP00000019679 | ENSMUSP00000105754 | Armadillo repeat-containing protein 6. | Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate. | 0.422 |
Armc6 | Tmem161a | ENSMUSP00000019679 | ENSMUSP00000002413 | Armadillo repeat-containing protein 6. | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.615 |
Asb14 | Klhl31 | ENSMUSP00000087810 | ENSMUSP00000059643 | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity). | 0.449 |
Asb14 | Tmem161a | ENSMUSP00000087810 | ENSMUSP00000002413 | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.576 |
Caskin2 | Tmem161a | ENSMUSP00000041328 | ENSMUSP00000002413 | Caskin-2. | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.520 |
Caskin2 | Tmem94 | ENSMUSP00000041328 | ENSMUSP00000091440 | Caskin-2. | Transmembrane protein 94. | 0.681 |
Klhl31 | Asb14 | ENSMUSP00000059643 | ENSMUSP00000087810 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity). | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | 0.449 |
Klhl31 | Popdc2 | ENSMUSP00000059643 | ENSMUSP00000023494 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity). | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density. | 0.572 |
Klhl31 | Tmem161a | ENSMUSP00000059643 | ENSMUSP00000002413 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity). | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.637 |
Klhl31 | Tmem38a | ENSMUSP00000059643 | ENSMUSP00000034244 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity). | Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. | 0.616 |
Nfatc4 | Tmem161a | ENSMUSP00000024179 | ENSMUSP00000002413 | Nuclear factor of activated T-cells, cytoplasmic 4; Ca(2+)-regulated transcription factor that is involved in several processes, including the development and function of the immune, cardiovascular, musculoskeletal, and nervous systems. Involved in T-cell activation, stimulating the transcription of cytokine genes, including that of IL2 and IL4. Along with NFATC3, involved in embryonic heart development. Involved in mitochondrial energy metabolism required for cardiac morphogenesis and function. Transactivates many genes involved in heart physiology. Along with GATA4, binds to and acti [...] | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.576 |
Popdc2 | Klhl31 | ENSMUSP00000023494 | ENSMUSP00000059643 | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density. | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity). | 0.572 |
Popdc2 | Tmem161a | ENSMUSP00000023494 | ENSMUSP00000002413 | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density. | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.652 |
Popdc2 | Tmem38a | ENSMUSP00000023494 | ENSMUSP00000034244 | Popeye domain-containing protein 2; Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density. | Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. | 0.564 |
Slc25a42 | Armc6 | ENSMUSP00000105754 | ENSMUSP00000019679 | Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate. | Armadillo repeat-containing protein 6. | 0.422 |
Slc25a42 | Tmem161a | ENSMUSP00000105754 | ENSMUSP00000002413 | Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate. | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.605 |
Slc25a42 | Tmem94 | ENSMUSP00000105754 | ENSMUSP00000091440 | Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate. | Transmembrane protein 94. | 0.516 |
Tmem161a | Armc6 | ENSMUSP00000002413 | ENSMUSP00000019679 | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | Armadillo repeat-containing protein 6. | 0.615 |
Tmem161a | Asb14 | ENSMUSP00000002413 | ENSMUSP00000087810 | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | Ankyrin repeat and SOCS box protein 14; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | 0.576 |
Tmem161a | Caskin2 | ENSMUSP00000002413 | ENSMUSP00000041328 | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | Caskin-2. | 0.520 |