STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ifrd2Interferon-related developmental regulator 2. (441 aa)    
Predicted Functional Partners:
Fau
Ubiquitin-like protein FUBI; Belongs to the ubiquitin family.
    
 
 0.978
Rpl18a
60S ribosomal protein L18a.
   
 
 0.707
Rpl8
60S ribosomal protein L8; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.701
Rpsa
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...]
   
   0.682
Rps7
40S ribosomal protein S7; Required for rRNA maturation.
   
 
 0.676
Rpl38
60S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
    
 
 0.676
Rps28
40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
    
 
 0.673
Rps20
40S ribosomal protein S20.
   
 
 0.672
Rps2
40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
   0.670
Rps16
40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.
   
   0.670
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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