node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cd33 | Mcemp1 | ENSMUSP00000004728 | ENSMUSP00000014118 | Myeloid cell surface antigen CD33; Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (By similarity). Preferentially binds sialic acid to the short O-linked glycans of certain mucins. | Mast cell-expressed membrane protein 1. | 0.418 |
Chil3 | Mcemp1 | ENSMUSP00000053923 | ENSMUSP00000014118 | Chitinase-like protein 3; Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds chitin and heparin. Has weak hexosaminidase activity but no chitinase activity. Has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils. May play a role in inflammation and allergy. | Mast cell-expressed membrane protein 1. | 0.568 |
Clec4d | Mcemp1 | ENSMUSP00000032240 | ENSMUSP00000014118 | C-type lectin domain family 4 member D; A calcium-dependent lectin involved in innate recognition of pathogen-associated molecular patterns (PAMPs). Interacts with signaling adapter Fc receptor gamma chain/FCER1G, likely via CLEC4E, to form a functional complex in antigen presenting cells. Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shapin [...] | Mast cell-expressed membrane protein 1. | 0.457 |
Fam102b | Mcemp1 | ENSMUSP00000131904 | ENSMUSP00000014118 | Protein FAM102B; Belongs to the FAM102 family. | Mast cell-expressed membrane protein 1. | 0.525 |
Fam102b | Pcp2 | ENSMUSP00000131904 | ENSMUSP00000121079 | Protein FAM102B; Belongs to the FAM102 family. | Purkinje cell protein 2; May function as a cell-type specific modulator for G protein- mediated cell signaling. | 0.568 |
Fam102b | Pet100 | ENSMUSP00000131904 | ENSMUSP00000137626 | Protein FAM102B; Belongs to the FAM102 family. | Protein PET100 homolog, mitochondrial; Belongs to the PET100 family. | 0.468 |
Fam102b | Trappc5 | ENSMUSP00000131904 | ENSMUSP00000146674 | Protein FAM102B; Belongs to the FAM102 family. | Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily. | 0.592 |
Mcemp1 | Cd33 | ENSMUSP00000014118 | ENSMUSP00000004728 | Mast cell-expressed membrane protein 1. | Myeloid cell surface antigen CD33; Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state (By similarity). Preferentially binds sialic acid to the short O-linked glycans of certain mucins. | 0.418 |
Mcemp1 | Chil3 | ENSMUSP00000014118 | ENSMUSP00000053923 | Mast cell-expressed membrane protein 1. | Chitinase-like protein 3; Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds chitin and heparin. Has weak hexosaminidase activity but no chitinase activity. Has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils. May play a role in inflammation and allergy. | 0.568 |
Mcemp1 | Clec4d | ENSMUSP00000014118 | ENSMUSP00000032240 | Mast cell-expressed membrane protein 1. | C-type lectin domain family 4 member D; A calcium-dependent lectin involved in innate recognition of pathogen-associated molecular patterns (PAMPs). Interacts with signaling adapter Fc receptor gamma chain/FCER1G, likely via CLEC4E, to form a functional complex in antigen presenting cells. Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shapin [...] | 0.457 |
Mcemp1 | Fam102b | ENSMUSP00000014118 | ENSMUSP00000131904 | Mast cell-expressed membrane protein 1. | Protein FAM102B; Belongs to the FAM102 family. | 0.525 |
Mcemp1 | Olfr670 | ENSMUSP00000014118 | ENSMUSP00000151138 | Mast cell-expressed membrane protein 1. | Olfactory receptor. | 0.489 |
Mcemp1 | Pcp2 | ENSMUSP00000014118 | ENSMUSP00000121079 | Mast cell-expressed membrane protein 1. | Purkinje cell protein 2; May function as a cell-type specific modulator for G protein- mediated cell signaling. | 0.566 |
Mcemp1 | Pet100 | ENSMUSP00000014118 | ENSMUSP00000137626 | Mast cell-expressed membrane protein 1. | Protein PET100 homolog, mitochondrial; Belongs to the PET100 family. | 0.585 |
Mcemp1 | Slc31a2 | ENSMUSP00000014118 | ENSMUSP00000081578 | Mast cell-expressed membrane protein 1. | Probable low affinity copper uptake protein 2; Involved in low-affinity copper uptake; Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily. | 0.405 |
Mcemp1 | Trappc5 | ENSMUSP00000014118 | ENSMUSP00000146674 | Mast cell-expressed membrane protein 1. | Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily. | 0.479 |
Mcemp1 | Trem3 | ENSMUSP00000014118 | ENSMUSP00000044478 | Mast cell-expressed membrane protein 1. | Triggering receptor expressed on myeloid cells 3; Forms a receptor signaling complex with TYROBP/DAP12 which mediates activation of macrophages as part of the innate immune response. | 0.423 |
Olfr670 | Mcemp1 | ENSMUSP00000151138 | ENSMUSP00000014118 | Olfactory receptor. | Mast cell-expressed membrane protein 1. | 0.489 |
Pcp2 | Fam102b | ENSMUSP00000121079 | ENSMUSP00000131904 | Purkinje cell protein 2; May function as a cell-type specific modulator for G protein- mediated cell signaling. | Protein FAM102B; Belongs to the FAM102 family. | 0.568 |
Pcp2 | Mcemp1 | ENSMUSP00000121079 | ENSMUSP00000014118 | Purkinje cell protein 2; May function as a cell-type specific modulator for G protein- mediated cell signaling. | Mast cell-expressed membrane protein 1. | 0.566 |