node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dnah12 | Dynlrb2 | ENSMUSP00000022433 | ENSMUSP00000077301 | Dynein heavy chain 12, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | 0.613 |
Dnah12 | Tppp3 | ENSMUSP00000022433 | ENSMUSP00000135040 | Dynein heavy chain 12, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.453 |
Dynlrb2 | Dnah12 | ENSMUSP00000077301 | ENSMUSP00000022433 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Dynein heavy chain 12, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). | 0.613 |
Dynlrb2 | Lrrc23 | ENSMUSP00000077301 | ENSMUSP00000032218 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Leucine-rich repeat-containing protein 23. | 0.686 |
Dynlrb2 | Pifo | ENSMUSP00000077301 | ENSMUSP00000010280 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Protein pitchfork; During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle- dependent manner. | 0.720 |
Dynlrb2 | Tppp3 | ENSMUSP00000077301 | ENSMUSP00000135040 | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.419 |
Itih3 | Tppp3 | ENSMUSP00000006697 | ENSMUSP00000135040 | Inter-alpha-trypsin inhibitor heavy chain H3; May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.407 |
Lrrc23 | Dynlrb2 | ENSMUSP00000032218 | ENSMUSP00000077301 | Leucine-rich repeat-containing protein 23. | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | 0.686 |
Lrrc23 | Scgb3a2 | ENSMUSP00000032218 | ENSMUSP00000140375 | Leucine-rich repeat-containing protein 23. | Secretoglobin family 3A member 2; Secreted cytokine-like protein (By similarity). Binds to the scavenger receptor MARCO (By similarity). Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram- negative bacterium P.aeruginosa, and yeast (By similarity). Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the p [...] | 0.434 |
Lrrc23 | Sftpb | ENSMUSP00000032218 | ENSMUSP00000138695 | Leucine-rich repeat-containing protein 23. | Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | 0.433 |
Lrrc23 | Tppp3 | ENSMUSP00000032218 | ENSMUSP00000135040 | Leucine-rich repeat-containing protein 23. | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.429 |
Mkx | Tppp3 | ENSMUSP00000078718 | ENSMUSP00000135040 | Homeobox protein Mohawk; May act as a morphogenetic regulator of cell adhesion. Participates in the early events that lead to differentiation. | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.416 |
Pifo | Dynlrb2 | ENSMUSP00000010280 | ENSMUSP00000077301 | Protein pitchfork; During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle- dependent manner. | Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules; Belongs to the GAMAD family. | 0.720 |
Pifo | Tppp3 | ENSMUSP00000010280 | ENSMUSP00000135040 | Protein pitchfork; During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle- dependent manner. | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.446 |
Scgb3a2 | Lrrc23 | ENSMUSP00000140375 | ENSMUSP00000032218 | Secretoglobin family 3A member 2; Secreted cytokine-like protein (By similarity). Binds to the scavenger receptor MARCO (By similarity). Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram- negative bacterium P.aeruginosa, and yeast (By similarity). Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the p [...] | Leucine-rich repeat-containing protein 23. | 0.434 |
Scgb3a2 | Sftpb | ENSMUSP00000140375 | ENSMUSP00000138695 | Secretoglobin family 3A member 2; Secreted cytokine-like protein (By similarity). Binds to the scavenger receptor MARCO (By similarity). Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram- negative bacterium P.aeruginosa, and yeast (By similarity). Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the p [...] | Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | 0.869 |
Scgb3a2 | Tppp3 | ENSMUSP00000140375 | ENSMUSP00000135040 | Secretoglobin family 3A member 2; Secreted cytokine-like protein (By similarity). Binds to the scavenger receptor MARCO (By similarity). Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram- negative bacterium P.aeruginosa, and yeast (By similarity). Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the p [...] | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.500 |
Sftpb | Lrrc23 | ENSMUSP00000138695 | ENSMUSP00000032218 | Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | Leucine-rich repeat-containing protein 23. | 0.433 |
Sftpb | Scgb3a2 | ENSMUSP00000138695 | ENSMUSP00000140375 | Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | Secretoglobin family 3A member 2; Secreted cytokine-like protein (By similarity). Binds to the scavenger receptor MARCO (By similarity). Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram- negative bacterium P.aeruginosa, and yeast (By similarity). Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium. Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the p [...] | 0.869 |
Sftpb | Tppp3 | ENSMUSP00000138695 | ENSMUSP00000135040 | Pulmonary surfactant-associated protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter. | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity (By similarity). Required for embryo implantation; possibly by regulating beta-catenin. Also required for decidualization via regulation of beta-catenin. Belongs to the TPPP family. | 0.437 |