node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
6820408C15Rik | Clvs1 | ENSMUSP00000037024 | ENSMUSP00000035649 | RIKEN cDNA 6820408C15 gene. | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | 0.626 |
6820408C15Rik | Unkl | ENSMUSP00000037024 | ENSMUSP00000039670 | RIKEN cDNA 6820408C15 gene. | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.607 |
6820408C15Rik | Zfp251 | ENSMUSP00000037024 | ENSMUSP00000079268 | RIKEN cDNA 6820408C15 gene. | Zinc finger protein 251. | 0.653 |
Adgra3 | Cerk | ENSMUSP00000030971 | ENSMUSP00000038203 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway. | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8- dihydroceramide), to a lesser extent on C2-ceramide and C6- dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides (By similarity). Binds phosphoinositides (By similarity). | 0.483 |
Adgra3 | Fam171a1 | ENSMUSP00000030971 | ENSMUSP00000110751 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway. | Family with sequence similarity 171, member A1. | 0.487 |
Adgra3 | Unkl | ENSMUSP00000030971 | ENSMUSP00000039670 | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway. | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.551 |
Btbd6 | Unkl | ENSMUSP00000002880 | ENSMUSP00000039670 | BTB/POZ domain-containing protein 6; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity). | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.459 |
Cerk | Adgra3 | ENSMUSP00000038203 | ENSMUSP00000030971 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8- dihydroceramide), to a lesser extent on C2-ceramide and C6- dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides (By similarity). Binds phosphoinositides (By similarity). | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway. | 0.483 |
Cerk | Unkl | ENSMUSP00000038203 | ENSMUSP00000039670 | Ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8- dihydroceramide), to a lesser extent on C2-ceramide and C6- dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides (By similarity). Binds phosphoinositides (By similarity). | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.455 |
Clvs1 | 6820408C15Rik | ENSMUSP00000035649 | ENSMUSP00000037024 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | RIKEN cDNA 6820408C15 gene. | 0.626 |
Clvs1 | Unkl | ENSMUSP00000035649 | ENSMUSP00000039670 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.485 |
Clvs1 | Zfp251 | ENSMUSP00000035649 | ENSMUSP00000079268 | Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity). | Zinc finger protein 251. | 0.470 |
Fam171a1 | Adgra3 | ENSMUSP00000110751 | ENSMUSP00000030971 | Family with sequence similarity 171, member A1. | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway. | 0.487 |
Fam171a1 | Unkl | ENSMUSP00000110751 | ENSMUSP00000039670 | Family with sequence similarity 171, member A1. | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.712 |
Fam49b | Unkl | ENSMUSP00000066359 | ENSMUSP00000039670 | Protein FAM49B. | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.456 |
Ino80c | Unkl | ENSMUSP00000114643 | ENSMUSP00000039670 | INO80 complex subunit C; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.456 |
Sh3tc1 | Unkl | ENSMUSP00000070610 | ENSMUSP00000039670 | SH3 domain and tetratricopeptide repeats 1. | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | 0.573 |
Unkl | 6820408C15Rik | ENSMUSP00000039670 | ENSMUSP00000037024 | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | RIKEN cDNA 6820408C15 gene. | 0.607 |
Unkl | Adgra3 | ENSMUSP00000039670 | ENSMUSP00000030971 | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | Adhesion G protein-coupled receptor A3; Orphan receptor that may have a role in planar cell polarity pathway. | 0.551 |
Unkl | Btbd6 | ENSMUSP00000039670 | ENSMUSP00000002880 | Putative E3 ubiquitin-protein ligase UNKL; May participate in a protein complex showing an E3 ligase activity regulated by Rac1. Ubiquitination is directed towards itself and possibly other substrates, such as Baf60b/Smarcd2. Intrinsic E3 ligase activity has not been proven; Belongs to the unkempt family. | BTB/POZ domain-containing protein 6; Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity). | 0.459 |