node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acaa1a | Acaa1b | ENSMUSP00000042351 | ENSMUSP00000010795 | 3-ketoacyl-CoA thiolase A, peroxisomal. | 3-ketoacyl-CoA thiolase B, peroxisomal. | 0.919 |
Acaa1a | Agps | ENSMUSP00000042351 | ENSMUSP00000041967 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.551 |
Acaa1a | Pex10 | ENSMUSP00000042351 | ENSMUSP00000099469 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. | 0.575 |
Acaa1a | Pex12 | ENSMUSP00000042351 | ENSMUSP00000018877 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisome assembly protein 12; Required for protein import into peroxisomes. | 0.433 |
Acaa1a | Pex13 | ENSMUSP00000042351 | ENSMUSP00000020523 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). | 0.663 |
Acaa1a | Pex14 | ENSMUSP00000042351 | ENSMUSP00000099506 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin. | 0.565 |
Acaa1a | Pex5 | ENSMUSP00000042351 | ENSMUSP00000108151 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.670 |
Acaa1a | Pex5l | ENSMUSP00000042351 | ENSMUSP00000142196 | 3-ketoacyl-CoA thiolase A, peroxisomal. | PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. Belongs to the peroxisomal targeting signal receptor family. | 0.480 |
Acaa1a | Pex6 | ENSMUSP00000042351 | ENSMUSP00000002840 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Probably required for protein import into peroxisomes. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (By similarity). | 0.685 |
Acaa1a | Pex7 | ENSMUSP00000042351 | ENSMUSP00000020182 | 3-ketoacyl-CoA thiolase A, peroxisomal. | Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. | 0.926 |
Acaa1b | Acaa1a | ENSMUSP00000010795 | ENSMUSP00000042351 | 3-ketoacyl-CoA thiolase B, peroxisomal. | 3-ketoacyl-CoA thiolase A, peroxisomal. | 0.919 |
Acaa1b | Agps | ENSMUSP00000010795 | ENSMUSP00000041967 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.718 |
Acaa1b | Pex10 | ENSMUSP00000010795 | ENSMUSP00000099469 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. | 0.768 |
Acaa1b | Pex12 | ENSMUSP00000010795 | ENSMUSP00000018877 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisome assembly protein 12; Required for protein import into peroxisomes. | 0.702 |
Acaa1b | Pex13 | ENSMUSP00000010795 | ENSMUSP00000020523 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). | 0.821 |
Acaa1b | Pex14 | ENSMUSP00000010795 | ENSMUSP00000099506 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin. | 0.773 |
Acaa1b | Pex5 | ENSMUSP00000010795 | ENSMUSP00000108151 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.792 |
Acaa1b | Pex5l | ENSMUSP00000010795 | ENSMUSP00000142196 | 3-ketoacyl-CoA thiolase B, peroxisomal. | PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence. Belongs to the peroxisomal targeting signal receptor family. | 0.456 |
Acaa1b | Pex6 | ENSMUSP00000010795 | ENSMUSP00000002840 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Probably required for protein import into peroxisomes. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (By similarity). | 0.614 |
Acaa1b | Pex7 | ENSMUSP00000010795 | ENSMUSP00000020182 | 3-ketoacyl-CoA thiolase B, peroxisomal. | Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. | 0.956 |