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Ddx50 protein (mouse) - STRING interaction network
"Ddx50" - ATP-dependent RNA helicase DDX50 in Mus musculus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
Ddx50ATP-dependent RNA helicase DDX50; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 (734 aa)    
Predicted Functional Partners:
Ascc3
Activating signal cointegrator 1 complex subunit 3; 3’-5’ DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3- methylcytosine (3mC) within double-stranded regions. Enhances NF- kappa-B, SRF and AP1 transactivation (By similarity) (2198 aa)
     
 
  0.833
Gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (634 aa)
     
 
  0.829
Dqx1
ATP-dependent RNA helicase DQX1; DEAQ RNA-dependent ATPase (718 aa)
     
 
  0.776
Pno1
RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3’-end of 18S rRNA (248 aa)
     
 
  0.755
Ddx56
Probable ATP-dependent RNA helicase DDX56; May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity (By similarity); Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily (546 aa)
   
 
0.737
Rsl1d1
Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage (452 aa)
     
 
  0.717
Nop56
Nucleolar protein 56; Involved in the early to middle stages of 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs (By similarity); Belongs to the NOP5/NOP56 family (580 aa)
   
 
  0.713
Dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37 (1150 aa)
     
 
  0.707
Nop58
Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity); Belongs to the NOP5/NOP56 family (536 aa)
   
 
  0.682
Nhp2
H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...] (153 aa)
     
 
  0.677
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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