Thap2 protein (mouse) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

Thap2

THAP domain-containing protein 2. (217 aa)

Predicted Functional Partners:

Thap11

0.624

Hcfc1

0.596

Rbm12b1

0.562

Zkscan7

0.529

Ofcc1

0.495

Tmem215

0.449

Hcfc2

0.411

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hcfc1	Hcfc2	ENSMUSP00000033761	ENSMUSP00000020478	HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (By similarity). Coactivator for EGR2 and GABP2 (By similarity). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]	Host cell factor 2.	0.970
Hcfc1	Thap11	ENSMUSP00000033761	ENSMUSP00000048994	HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (By similarity). Coactivator for EGR2 and GABP2 (By similarity). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]	THAP domain-containing protein 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.	0.839
Hcfc1	Thap2	ENSMUSP00000033761	ENSMUSP00000151353	HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (By similarity). Coactivator for EGR2 and GABP2 (By similarity). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]	THAP domain-containing protein 2.	0.596
Hcfc2	Hcfc1	ENSMUSP00000020478	ENSMUSP00000033761	Host cell factor 2.	HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (By similarity). Coactivator for EGR2 and GABP2 (By similarity). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]	0.970
Hcfc2	Thap2	ENSMUSP00000020478	ENSMUSP00000151353	Host cell factor 2.	THAP domain-containing protein 2.	0.411
Ofcc1	Thap2	ENSMUSP00000062217	ENSMUSP00000151353	Orofacial cleft 1 candidate gene 1 protein homolog.	THAP domain-containing protein 2.	0.495
Rbm12b1	Thap2	ENSMUSP00000064195	ENSMUSP00000151353	RNA-binding protein 12B-A.	THAP domain-containing protein 2.	0.562
Thap11	Hcfc1	ENSMUSP00000048994	ENSMUSP00000033761	THAP domain-containing protein 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.	HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (By similarity). Coactivator for EGR2 and GABP2 (By similarity). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]	0.839
Thap11	Thap2	ENSMUSP00000048994	ENSMUSP00000151353	THAP domain-containing protein 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.	THAP domain-containing protein 2.	0.624
Thap2	Hcfc1	ENSMUSP00000151353	ENSMUSP00000033761	THAP domain-containing protein 2.	HCF C-terminal chain 1; Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300 (By similarity). Coactivator for EGR2 and GABP2 (By similarity). Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription respectively) together (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal hist [...]	0.596
Thap2	Hcfc2	ENSMUSP00000151353	ENSMUSP00000020478	THAP domain-containing protein 2.	Host cell factor 2.	0.411
Thap2	Ofcc1	ENSMUSP00000151353	ENSMUSP00000062217	THAP domain-containing protein 2.	Orofacial cleft 1 candidate gene 1 protein homolog.	0.495
Thap2	Rbm12b1	ENSMUSP00000151353	ENSMUSP00000064195	THAP domain-containing protein 2.	RNA-binding protein 12B-A.	0.562
Thap2	Thap11	ENSMUSP00000151353	ENSMUSP00000048994	THAP domain-containing protein 2.	THAP domain-containing protein 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.	0.624
Thap2	Tmem215	ENSMUSP00000151353	ENSMUSP00000052129	THAP domain-containing protein 2.	Transmembrane protein 215.	0.449
Thap2	Zkscan7	ENSMUSP00000151353	ENSMUSP00000071695	THAP domain-containing protein 2.	Zinc finger with KRAB and SCAN domains 7.	0.529
Tmem215	Thap2	ENSMUSP00000052129	ENSMUSP00000151353	Transmembrane protein 215.	THAP domain-containing protein 2.	0.449
Zkscan7	Thap2	ENSMUSP00000071695	ENSMUSP00000151353	Zinc finger with KRAB and SCAN domains 7.	THAP domain-containing protein 2.	0.529