STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc5a4aSolute carrier family 5 member 4A; Has sugar-induced sodium-independent electrogenic activity. Generation of glucose-induced inward currents is pH-dependent, with activity in acidic conditions (pH 5) but not neutral conditions. Does not have sugar transport activity; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (656 aa)    
Predicted Functional Partners:
Spopfm3
Speckle-type BTB/POZ protein family member 3.
      
 0.607
Gm20708
Predicted gene 20708.
      
 0.607
Fam205a2
Mus musculus family with sequence similarity 205, member A2 (Fam205a2), transcript variant 2, mRNA.
      
 0.606
Fam205a3
Family with sequence similarity 205, member A3.
      
 0.606
Fam205a4
Protein FAM205A-2.
      
 0.552
Fam205a2-2
Family with sequence similarity 205, member A2.
      
 0.552
Aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.531
Slc2a7
Solute carrier family 2, facilitated glucose transporter member 7; Probable sugar transporter. Its physiological substrate is subject to discussion. Does not transport galactose, 2-deoxy-d-glucose and xylose; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
   
  
 0.525
Gfod2
Glucose-fructose oxidoreductase domain-containing protein 2; Promotes matrix assembly; Belongs to the Gfo/Idh/MocA family.
     
 0.524
Tgds
dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
     
 0.521
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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