STRINGSTRING
Cox11 protein (mouse) - STRING interaction network
"Cox11" - COX11 homolog, cytochrome c oxidase assembly protein in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cox11COX11 homolog, cytochrome c oxidase assembly protein (yeast); Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (275 aa)    
Predicted Functional Partners:
Cox15
COX15 homolog, cytochrome c oxidase assembly protein (yeast); May be involved in the biosynthesis of heme A (413 aa)
   
 
  0.890
mt-Co2
Mitochondrially encoded cytochrome c oxidase II; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1 (227 aa)
 
 
  0.889
Cox17a
Cytochrome c oxidase copper chaperone ; Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity) (63 aa)
     
   
  0.881
Cox17
Cytochrome c oxidase, subunit XVII assembly protein homolog (yeast) (63 aa)
     
   
  0.881
Surf1
Surfeit gene 1; Probably involved in the biogenesis of the COX complex (306 aa)
   
 
  0.857
Cox10
COX10 homolog, cytochrome c oxidase assembly protein, heme A- farnesyltransferase (yeast); Converts protoheme IX and farnesyl diphosphate to heme O (443 aa)
   
 
  0.854
Sco2
SCO cytochrome oxidase deficient homolog 2 (yeast); Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2) (255 aa)
   
 
  0.839
mt-Co3
Mitochondrially encoded cytochrome c oxidase III; Subunits I, II and III form the functional core of the enzyme complex (261 aa)
 
 
  0.824
Cox19
COX19 cytochrome c oxidase assembly homolog (S. cerevisiae); May be required for the assembly of mitochondrial cytochrome c oxidase (92 aa)
     
   
  0.813
mt-Co1
Mitochondrially encoded cytochrome c oxidase I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (514 aa)
 
 
  0.805
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mice, mouse, nude mice, transgenic mice
Server load: low (11%) [HD]