node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ankrd55 | Lratd1 | ENSMUSP00000022275 | ENSMUSP00000020926 | Ankyrin repeat domain-containing protein 55. | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 0.599 |
Dact2 | Lratd1 | ENSMUSP00000051638 | ENSMUSP00000020926 | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling. | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 0.593 |
Dop1a | Lratd1 | ENSMUSP00000140740 | ENSMUSP00000020926 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes. | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 0.529 |
Dop1a | Resf1 | ENSMUSP00000140740 | ENSMUSP00000041180 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes. | Retroelement silencing factor 1; Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells. | 0.526 |
Fam49a | Lratd1 | ENSMUSP00000065613 | ENSMUSP00000020926 | Protein FAM49A; Belongs to the FAM49 family. | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 0.650 |
Fam49a | Ppp1r1a | ENSMUSP00000065613 | ENSMUSP00000023133 | Protein FAM49A; Belongs to the FAM49 family. | Protein phosphatase 1 regulatory subunit 1A; Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. | 0.436 |
Lratd1 | Ankrd55 | ENSMUSP00000020926 | ENSMUSP00000022275 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Ankyrin repeat domain-containing protein 55. | 0.599 |
Lratd1 | Dact2 | ENSMUSP00000020926 | ENSMUSP00000051638 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling. | 0.593 |
Lratd1 | Dop1a | ENSMUSP00000020926 | ENSMUSP00000140740 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes. | 0.529 |
Lratd1 | Fam49a | ENSMUSP00000020926 | ENSMUSP00000065613 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Protein FAM49A; Belongs to the FAM49 family. | 0.650 |
Lratd1 | Nt5dc2 | ENSMUSP00000020926 | ENSMUSP00000087680 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 5'-nucleotidase domain-containing 2. | 0.532 |
Lratd1 | Plaat1 | ENSMUSP00000020926 | ENSMUSP00000087257 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Phospholipase A and acyltransferase 1; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylchol [...] | 0.694 |
Lratd1 | Ppp1r1a | ENSMUSP00000020926 | ENSMUSP00000023133 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Protein phosphatase 1 regulatory subunit 1A; Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. | 0.552 |
Lratd1 | Resf1 | ENSMUSP00000020926 | ENSMUSP00000041180 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Retroelement silencing factor 1; Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells. | 0.523 |
Lratd1 | Smc6 | ENSMUSP00000020926 | ENSMUSP00000020931 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Structural maintenance of chromosomes protein 6; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity). | 0.533 |
Lratd1 | Stk32a | ENSMUSP00000020926 | ENSMUSP00000038471 | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | Serine/threonine-protein kinase 32A. | 0.537 |
Nt5dc2 | Lratd1 | ENSMUSP00000087680 | ENSMUSP00000020926 | 5'-nucleotidase domain-containing 2. | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 0.532 |
Nt5dc2 | Resf1 | ENSMUSP00000087680 | ENSMUSP00000041180 | 5'-nucleotidase domain-containing 2. | Retroelement silencing factor 1; Plays a role in the regulation of imprinted gene expression, regulates repressive epigenetic modifications associated with SETDB1. Required for the recruitment or accumulation of SETDB1 to the endogenous retroviruses (ERVs) and maintenance of repressive chromatin configuration, contributing to a subset of the SETDB1-dependent ERV silencing in embryonic stem cells. | 0.413 |
Plaat1 | Lratd1 | ENSMUSP00000087257 | ENSMUSP00000020926 | Phospholipase A and acyltransferase 1; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylchol [...] | Protein LRATD1; May play a role in cell morphology and motility. Belongs to the LRATD family. | 0.694 |
Ppp1r1a | Fam49a | ENSMUSP00000023133 | ENSMUSP00000065613 | Protein phosphatase 1 regulatory subunit 1A; Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. | Protein FAM49A; Belongs to the FAM49 family. | 0.436 |