node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ddx18 | Ebna1bp2 | ENSMUSP00000001724 | ENSMUSP00000030501 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.982 |
Ddx18 | Ftsj3 | ENSMUSP00000001724 | ENSMUSP00000021048 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.990 |
Ddx18 | Mak16 | ENSMUSP00000001724 | ENSMUSP00000033983 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Protein MAK16 homolog. | 0.968 |
Ddx18 | Nifk | ENSMUSP00000001724 | ENSMUSP00000027626 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.999 |
Ddx18 | Noc2l | ENSMUSP00000001724 | ENSMUSP00000137253 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.995 |
Ddx18 | Nop53 | ENSMUSP00000001724 | ENSMUSP00000043981 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Ribosome biogenesis protein NOP53; Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may also play a role in rRNA transcription (By similarity). Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions. DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and all [...] | 0.601 |
Ddx18 | Nop58 | ENSMUSP00000001724 | ENSMUSP00000140250 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity). Belongs to the NOP5/NOP56 family. | 0.987 |
Ddx18 | Pes1 | ENSMUSP00000001724 | ENSMUSP00000020705 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.997 |
Ddx18 | Wdr12 | ENSMUSP00000001724 | ENSMUSP00000027173 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.995 |
Ddx18 | Wdr74 | ENSMUSP00000001724 | ENSMUSP00000043315 | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.993 |
Ebna1bp2 | Ddx18 | ENSMUSP00000030501 | ENSMUSP00000001724 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | 0.982 |
Ebna1bp2 | Ftsj3 | ENSMUSP00000030501 | ENSMUSP00000021048 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.996 |
Ebna1bp2 | Mak16 | ENSMUSP00000030501 | ENSMUSP00000033983 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Protein MAK16 homolog. | 0.994 |
Ebna1bp2 | Nifk | ENSMUSP00000030501 | ENSMUSP00000027626 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.998 |
Ebna1bp2 | Noc2l | ENSMUSP00000030501 | ENSMUSP00000137253 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.997 |
Ebna1bp2 | Nop53 | ENSMUSP00000030501 | ENSMUSP00000043981 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein NOP53; Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may also play a role in rRNA transcription (By similarity). Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions. DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and all [...] | 0.963 |
Ebna1bp2 | Nop58 | ENSMUSP00000030501 | ENSMUSP00000140250 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs (By similarity). Belongs to the NOP5/NOP56 family. | 0.966 |
Ebna1bp2 | Pes1 | ENSMUSP00000030501 | ENSMUSP00000020705 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Ebna1bp2 | Wdr12 | ENSMUSP00000030501 | ENSMUSP00000027173 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.993 |
Ebna1bp2 | Wdr74 | ENSMUSP00000030501 | ENSMUSP00000043315 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.992 |