STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc35b1Solute carrier family 35 member B1; Probable sugar transporter; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily. (322 aa)    
Predicted Functional Partners:
Pwp2
Periodic tryptophan protein 2 homolog.
 
 
    0.891
Slc35a2
UDP-galactose translocator; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
   
  
 0.718
Slc35d1
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N- acetylgalactosamine (UDP-GalNAc) from the cytoplasm into the endoplasmic reticulum lumen. Plays a role in chondroitin sulfate biosynthesis, which is important for formation of cartilage extracellular matrix and normal skeletal development. Belongs to the TPT transporter family. SLC35D subfamily.
   
  
 0.710
Fam117a
Protein FAM117A.
 
    
 0.697
Slc35a4
Probable UDP-sugar transporter protein SLC35A4.
   
  
 0.664
Tmem208
Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
   
 
 0.661
Slc35a5
Probable UDP-sugar transporter protein SLC35A5.
   
  
 0.644
Slc35c1
GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily.
   
  
 0.591
Dnajb11
DnaJ homolog subfamily B member 11; As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1.
   
  
 0.583
Yipf5
Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family.
   
  
 0.579
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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