node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adgb | Mb | ENSMUSP00000045452 | ENSMUSP00000125995 | Androglobin; Belongs to the peptidase C2 family. | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | 0.755 |
Adgb | Ngb | ENSMUSP00000045452 | ENSMUSP00000105806 | Androglobin; Belongs to the peptidase C2 family. | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti- apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. | 0.859 |
Adgb | Papln | ENSMUSP00000045452 | ENSMUSP00000113806 | Androglobin; Belongs to the peptidase C2 family. | Papilin. | 0.461 |
Aopep | Papln | ENSMUSP00000089148 | ENSMUSP00000113806 | Aminopeptidase O; Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. | Papilin. | 0.477 |
Fam149a | Papln | ENSMUSP00000091245 | ENSMUSP00000113806 | Protein FAM149A; Belongs to the FAM149 family. | Papilin. | 0.474 |
Fam149a | R3hcc1 | ENSMUSP00000091245 | ENSMUSP00000113898 | Protein FAM149A; Belongs to the FAM149 family. | R3H and coiled-coil domain-containing protein 1. | 0.536 |
Fbn1 | Papln | ENSMUSP00000099524 | ENSMUSP00000113806 | Fibrillin-1; [Fibrillin-1]: Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus [...] | Papilin. | 0.612 |
Mb | Adgb | ENSMUSP00000125995 | ENSMUSP00000045452 | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | Androglobin; Belongs to the peptidase C2 family. | 0.755 |
Mb | Ngb | ENSMUSP00000125995 | ENSMUSP00000105806 | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti- apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. | 0.913 |
Mb | Papln | ENSMUSP00000125995 | ENSMUSP00000113806 | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | Papilin. | 0.465 |
Ngb | Adgb | ENSMUSP00000105806 | ENSMUSP00000045452 | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti- apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. | Androglobin; Belongs to the peptidase C2 family. | 0.859 |
Ngb | Mb | ENSMUSP00000105806 | ENSMUSP00000125995 | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti- apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | 0.913 |
Ngb | Papln | ENSMUSP00000105806 | ENSMUSP00000113806 | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti- apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. | Papilin. | 0.461 |
Papln | Adgb | ENSMUSP00000113806 | ENSMUSP00000045452 | Papilin. | Androglobin; Belongs to the peptidase C2 family. | 0.461 |
Papln | Aopep | ENSMUSP00000113806 | ENSMUSP00000089148 | Papilin. | Aminopeptidase O; Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. | 0.477 |
Papln | Fam149a | ENSMUSP00000113806 | ENSMUSP00000091245 | Papilin. | Protein FAM149A; Belongs to the FAM149 family. | 0.474 |
Papln | Fbn1 | ENSMUSP00000113806 | ENSMUSP00000099524 | Papilin. | Fibrillin-1; [Fibrillin-1]: Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus [...] | 0.612 |
Papln | Mb | ENSMUSP00000113806 | ENSMUSP00000125995 | Papilin. | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | 0.465 |
Papln | Ngb | ENSMUSP00000113806 | ENSMUSP00000105806 | Papilin. | Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti- apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. | 0.461 |
Papln | R3hcc1 | ENSMUSP00000113806 | ENSMUSP00000113898 | Papilin. | R3H and coiled-coil domain-containing protein 1. | 0.470 |