node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Casr | Gcm2 | ENSMUSP00000069080 | ENSMUSP00000021791 | Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (By similarity). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino [...] | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.679 |
Casr | Pth | ENSMUSP00000069080 | ENSMUSP00000078723 | Extracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis (By similarity). Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system (By similarity). The G-protein-coupled receptor activity is activated by a co-agonist mechanism: aromatic amino [...] | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | 0.846 |
Cdx2 | Ctsq | ENSMUSP00000031650 | ENSMUSP00000021888 | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | Cathepsin Q; Belongs to the peptidase C1 family. | 0.409 |
Cdx2 | Gcm1 | ENSMUSP00000031650 | ENSMUSP00000024104 | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | 0.652 |
Cdx2 | Gcm2 | ENSMUSP00000031650 | ENSMUSP00000021791 | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.641 |
Cdx2 | Prl3d1 | ENSMUSP00000031650 | ENSMUSP00000152890 | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | Prolactin-3D1; Belongs to the somatotropin/prolactin family. | 0.516 |
Cdx2 | Tpbpa | ENSMUSP00000031650 | ENSMUSP00000021885 | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy. | 0.648 |
Ctsq | Cdx2 | ENSMUSP00000021888 | ENSMUSP00000031650 | Cathepsin Q; Belongs to the peptidase C1 family. | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | 0.409 |
Ctsq | Gcm1 | ENSMUSP00000021888 | ENSMUSP00000024104 | Cathepsin Q; Belongs to the peptidase C1 family. | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | 0.742 |
Ctsq | Gcm2 | ENSMUSP00000021888 | ENSMUSP00000021791 | Cathepsin Q; Belongs to the peptidase C1 family. | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.716 |
Ctsq | Gm27179 | ENSMUSP00000021888 | ENSMUSP00000139267 | Cathepsin Q; Belongs to the peptidase C1 family. | Predicted gene 27179. | 0.695 |
Ctsq | Prl3d1 | ENSMUSP00000021888 | ENSMUSP00000152890 | Cathepsin Q; Belongs to the peptidase C1 family. | Prolactin-3D1; Belongs to the somatotropin/prolactin family. | 0.716 |
Ctsq | Tpbpa | ENSMUSP00000021888 | ENSMUSP00000021885 | Cathepsin Q; Belongs to the peptidase C1 family. | Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy. | 0.492 |
Foxi3 | Gcm2 | ENSMUSP00000065664 | ENSMUSP00000021791 | Forkhead box I3. | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.637 |
Foxn1 | Gcm2 | ENSMUSP00000103929 | ENSMUSP00000021791 | Forkhead box protein N1; Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, includin [...] | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.720 |
Gcm1 | Cdx2 | ENSMUSP00000024104 | ENSMUSP00000031650 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Homeobox protein CDX-2; Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA; Belongs to the Caudal homeobox family. | 0.652 |
Gcm1 | Ctsq | ENSMUSP00000024104 | ENSMUSP00000021888 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Cathepsin Q; Belongs to the peptidase C1 family. | 0.742 |
Gcm1 | Gcm2 | ENSMUSP00000024104 | ENSMUSP00000021791 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.919 |
Gcm1 | Gm27179 | ENSMUSP00000024104 | ENSMUSP00000139267 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Predicted gene 27179. | 0.703 |
Gcm1 | Prl3d1 | ENSMUSP00000024104 | ENSMUSP00000152890 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Prolactin-3D1; Belongs to the somatotropin/prolactin family. | 0.678 |