node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
1110008P14Rik | 1700021F05Rik | ENSMUSP00000038970 | ENSMUSP00000119053 | UPF0184 protein C9orf16 homolog; Belongs to the UPF0184 (EST00098) family. | Mitochondrial transcription rescue factor 1; Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability. | 0.745 |
1110008P14Rik | Oxnad1 | ENSMUSP00000038970 | ENSMUSP00000022462 | UPF0184 protein C9orf16 homolog; Belongs to the UPF0184 (EST00098) family. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.644 |
1700021F05Rik | 1110008P14Rik | ENSMUSP00000119053 | ENSMUSP00000038970 | Mitochondrial transcription rescue factor 1; Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability. | UPF0184 protein C9orf16 homolog; Belongs to the UPF0184 (EST00098) family. | 0.745 |
1700021F05Rik | Oxnad1 | ENSMUSP00000119053 | ENSMUSP00000022462 | Mitochondrial transcription rescue factor 1; Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.548 |
Cps1 | Dhodh | ENSMUSP00000027144 | ENSMUSP00000115934 | Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | 0.773 |
Cps1 | Dpyd | ENSMUSP00000027144 | ENSMUSP00000039429 | Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | 0.747 |
Cps1 | Oxnad1 | ENSMUSP00000027144 | ENSMUSP00000022462 | Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.580 |
Cps1 | Umps | ENSMUSP00000027144 | ENSMUSP00000023510 | Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.851 |
Dhodh | Cps1 | ENSMUSP00000115934 | ENSMUSP00000027144 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | 0.773 |
Dhodh | Dpyd | ENSMUSP00000115934 | ENSMUSP00000039429 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | 0.490 |
Dhodh | Fads6 | ENSMUSP00000115934 | ENSMUSP00000058783 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Fatty acid desaturase 6. | 0.528 |
Dhodh | Fdxr | ENSMUSP00000115934 | ENSMUSP00000021078 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C- 27 hydroxylation in the liver. | 0.590 |
Dhodh | Oxnad1 | ENSMUSP00000115934 | ENSMUSP00000022462 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.821 |
Dhodh | Umps | ENSMUSP00000115934 | ENSMUSP00000023510 | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | Orotidine 5'-phosphate decarboxylase; In the C-terminal section; belongs to the OMP decarboxylase family. | 0.998 |
Dph3 | Oxnad1 | ENSMUSP00000068491 | ENSMUSP00000022462 | DPH3 homolog; Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2; Belongs to the DPH3 family. | Oxidoreductase NAD-binding domain-containing protein 1. | 0.746 |
Dpyd | Cps1 | ENSMUSP00000039429 | ENSMUSP00000027144 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | Carbamoyl-phosphate synthase [ammonia], mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell. | 0.747 |
Dpyd | Dhodh | ENSMUSP00000039429 | ENSMUSP00000115934 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | Dihydroorotate dehydrogenase (quinone), mitochondrial; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | 0.490 |
Dpyd | Fads6 | ENSMUSP00000039429 | ENSMUSP00000058783 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | Fatty acid desaturase 6. | 0.541 |
Dpyd | Fdxr | ENSMUSP00000039429 | ENSMUSP00000021078 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C- 27 hydroxylation in the liver. | 0.560 |
Dpyd | Oxnad1 | ENSMUSP00000039429 | ENSMUSP00000022462 | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). | Oxidoreductase NAD-binding domain-containing protein 1. | 0.826 |