node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adam32 | Lrrc63 | ENSMUSP00000113627 | ENSMUSP00000022574 | Disintegrin and metalloproteinase domain-containing protein 32; May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein. | Leucine-rich repeat-containing protein 63. | 0.506 |
Adam34l | Ankrd60 | ENSMUSP00000058858 | ENSMUSP00000113291 | A disintegrin and metallopeptidase domain 34-like. | Ankyrin repeat domain 60. | 0.487 |
Adam34l | Lrrc63 | ENSMUSP00000058858 | ENSMUSP00000022574 | A disintegrin and metallopeptidase domain 34-like. | Leucine-rich repeat-containing protein 63. | 0.615 |
Adgrl1 | Lrrc63 | ENSMUSP00000118452 | ENSMUSP00000022574 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat-containing protein 63. | 0.526 |
Adgrl2 | Lrrc63 | ENSMUSP00000143626 | ENSMUSP00000022574 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | Leucine-rich repeat-containing protein 63. | 0.526 |
Adgrl3 | Lrrc63 | ENSMUSP00000072336 | ENSMUSP00000022574 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | Leucine-rich repeat-containing protein 63. | 0.526 |
Ankrd60 | Adam34l | ENSMUSP00000113291 | ENSMUSP00000058858 | Ankyrin repeat domain 60. | A disintegrin and metallopeptidase domain 34-like. | 0.487 |
Ankrd60 | Lrrc63 | ENSMUSP00000113291 | ENSMUSP00000022574 | Ankyrin repeat domain 60. | Leucine-rich repeat-containing protein 63. | 0.815 |
Ankrd60 | Ttll8 | ENSMUSP00000113291 | ENSMUSP00000104996 | Ankyrin repeat domain 60. | Protein monoglycylase TTLL8; Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction. | 0.620 |
Lrrc63 | Adam32 | ENSMUSP00000022574 | ENSMUSP00000113627 | Leucine-rich repeat-containing protein 63. | Disintegrin and metalloproteinase domain-containing protein 32; May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein. | 0.506 |
Lrrc63 | Adam34l | ENSMUSP00000022574 | ENSMUSP00000058858 | Leucine-rich repeat-containing protein 63. | A disintegrin and metallopeptidase domain 34-like. | 0.615 |
Lrrc63 | Adgrl1 | ENSMUSP00000022574 | ENSMUSP00000118452 | Leucine-rich repeat-containing protein 63. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.526 |
Lrrc63 | Adgrl2 | ENSMUSP00000022574 | ENSMUSP00000143626 | Leucine-rich repeat-containing protein 63. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | 0.526 |
Lrrc63 | Adgrl3 | ENSMUSP00000022574 | ENSMUSP00000072336 | Leucine-rich repeat-containing protein 63. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | 0.526 |
Lrrc63 | Ankrd60 | ENSMUSP00000022574 | ENSMUSP00000113291 | Leucine-rich repeat-containing protein 63. | Ankyrin repeat domain 60. | 0.815 |
Lrrc63 | Mgat4d | ENSMUSP00000022574 | ENSMUSP00000041629 | Leucine-rich repeat-containing protein 63. | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; [Isoform 2]: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis. | 0.556 |
Lrrc63 | Paqr9 | ENSMUSP00000022574 | ENSMUSP00000078547 | Leucine-rich repeat-containing protein 63. | Membrane progesterone receptor epsilon; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. May be involved in regulating rapid P4 signaling in the nervous system. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Belongs to the ADIPOR family. | 0.523 |
Lrrc63 | Prtg | ENSMUSP00000022574 | ENSMUSP00000055815 | Leucine-rich repeat-containing protein 63. | Protogenin; May play a role in anteroposterior axis elongation. | 0.549 |
Lrrc63 | Ttll8 | ENSMUSP00000022574 | ENSMUSP00000104996 | Leucine-rich repeat-containing protein 63. | Protein monoglycylase TTLL8; Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction. | 0.714 |
Mgat4d | Lrrc63 | ENSMUSP00000041629 | ENSMUSP00000022574 | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D; [Isoform 2]: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis. | Leucine-rich repeat-containing protein 63. | 0.556 |