node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bbs9 | Fam118a | ENSMUSP00000122058 | ENSMUSP00000154985 | Protein PTHB1; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF [...] | Protein FAM118A; Belongs to the FAM118 family. | 0.537 |
Bbs9 | Letm2 | ENSMUSP00000122058 | ENSMUSP00000078160 | Protein PTHB1; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF [...] | LETM1 domain-containing protein LETM2, mitochondrial. | 0.453 |
Bbs9 | Rhbdd3 | ENSMUSP00000122058 | ENSMUSP00000099131 | Protein PTHB1; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF [...] | Rhomboid domain-containing protein 3. | 0.533 |
Dnajc18 | Fam118a | ENSMUSP00000025208 | ENSMUSP00000154985 | DnaJ homolog subfamily C member 18. | Protein FAM118A; Belongs to the FAM118 family. | 0.686 |
Dnajc18 | Letm2 | ENSMUSP00000025208 | ENSMUSP00000078160 | DnaJ homolog subfamily C member 18. | LETM1 domain-containing protein LETM2, mitochondrial. | 0.525 |
Dnajc18 | Pld6 | ENSMUSP00000025208 | ENSMUSP00000115503 | DnaJ homolog subfamily C member 18. | Mitochondrial cardiolipin hydrolase; Endonuclease that plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis. piRNAs provide essential protection against the activity of mobile genetic elements. piRNA- mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface. Although it cannot be excluded that it can act as [...] | 0.462 |
Dnajc18 | Reep6 | ENSMUSP00000025208 | ENSMUSP00000100991 | DnaJ homolog subfamily C member 18. | Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development. In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis. May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane. | 0.492 |
Dnajc18 | Rhbdd3 | ENSMUSP00000025208 | ENSMUSP00000099131 | DnaJ homolog subfamily C member 18. | Rhomboid domain-containing protein 3. | 0.533 |
Dnajc18 | Tmem39b | ENSMUSP00000025208 | ENSMUSP00000099648 | DnaJ homolog subfamily C member 18. | Transmembrane protein 39B. | 0.541 |
Erich1 | Fam118a | ENSMUSP00000106436 | ENSMUSP00000154985 | Glutamate-rich 1. | Protein FAM118A; Belongs to the FAM118 family. | 0.616 |
Erich1 | Olfr1426 | ENSMUSP00000106436 | ENSMUSP00000151331 | Glutamate-rich 1. | Olfactory receptor. | 0.520 |
Fam118a | Bbs9 | ENSMUSP00000154985 | ENSMUSP00000122058 | Protein FAM118A; Belongs to the FAM118 family. | Protein PTHB1; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF [...] | 0.537 |
Fam118a | Dnajc18 | ENSMUSP00000154985 | ENSMUSP00000025208 | Protein FAM118A; Belongs to the FAM118 family. | DnaJ homolog subfamily C member 18. | 0.686 |
Fam118a | Erich1 | ENSMUSP00000154985 | ENSMUSP00000106436 | Protein FAM118A; Belongs to the FAM118 family. | Glutamate-rich 1. | 0.616 |
Fam118a | Letm2 | ENSMUSP00000154985 | ENSMUSP00000078160 | Protein FAM118A; Belongs to the FAM118 family. | LETM1 domain-containing protein LETM2, mitochondrial. | 0.651 |
Fam118a | Olfr1426 | ENSMUSP00000154985 | ENSMUSP00000151331 | Protein FAM118A; Belongs to the FAM118 family. | Olfactory receptor. | 0.527 |
Fam118a | Pld6 | ENSMUSP00000154985 | ENSMUSP00000115503 | Protein FAM118A; Belongs to the FAM118 family. | Mitochondrial cardiolipin hydrolase; Endonuclease that plays a critical role in PIWI-interacting RNA (piRNA) biogenesis during spermatogenesis. piRNAs provide essential protection against the activity of mobile genetic elements. piRNA- mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface. Although it cannot be excluded that it can act as [...] | 0.545 |
Fam118a | Reep6 | ENSMUSP00000154985 | ENSMUSP00000100991 | Protein FAM118A; Belongs to the FAM118 family. | Receptor expression-enhancing protein 6; Required for correct function and survival of retinal photoreceptors. Required for retinal development. In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis. May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane. | 0.544 |
Fam118a | Rhbdd3 | ENSMUSP00000154985 | ENSMUSP00000099131 | Protein FAM118A; Belongs to the FAM118 family. | Rhomboid domain-containing protein 3. | 0.671 |
Fam118a | Tmem39b | ENSMUSP00000154985 | ENSMUSP00000099648 | Protein FAM118A; Belongs to the FAM118 family. | Transmembrane protein 39B. | 0.664 |