node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gadd45gip1 | Mrpl12 | ENSMUSP00000037783 | ENSMUSP00000044417 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 0.893 |
Gadd45gip1 | Mrpl15 | ENSMUSP00000037783 | ENSMUSP00000115512 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L15, mitochondrial. | 0.921 |
Gadd45gip1 | Mrpl28 | ENSMUSP00000037783 | ENSMUSP00000025014 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L28, mitochondrial; Belongs to the bacterial ribosomal protein bL28 family. | 0.940 |
Gadd45gip1 | Mrpl3 | ENSMUSP00000037783 | ENSMUSP00000035177 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family. | 0.838 |
Gadd45gip1 | Mrpl4 | ENSMUSP00000037783 | ENSMUSP00000003386 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.939 |
Gadd45gip1 | Mrpl41 | ENSMUSP00000037783 | ENSMUSP00000043561 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. | 0.922 |
Gadd45gip1 | Mrpl47 | ENSMUSP00000037783 | ENSMUSP00000048078 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family. | 0.917 |
Gadd45gip1 | Mrpl9 | ENSMUSP00000037783 | ENSMUSP00000029786 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 39S ribosomal protein L9, mitochondrial; Belongs to the bacterial ribosomal protein bL9 family. | 0.917 |
Gadd45gip1 | Mrps18a | ENSMUSP00000037783 | ENSMUSP00000024763 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 28S ribosomal protein S18a, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily. | 0.868 |
Gadd45gip1 | Mrps26 | ENSMUSP00000037783 | ENSMUSP00000123324 | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 28S ribosomal protein S26, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS26 family. | 0.862 |
Mrpl12 | Gadd45gip1 | ENSMUSP00000044417 | ENSMUSP00000037783 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. | 0.893 |
Mrpl12 | Mrpl15 | ENSMUSP00000044417 | ENSMUSP00000115512 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L15, mitochondrial. | 0.968 |
Mrpl12 | Mrpl28 | ENSMUSP00000044417 | ENSMUSP00000025014 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L28, mitochondrial; Belongs to the bacterial ribosomal protein bL28 family. | 0.942 |
Mrpl12 | Mrpl3 | ENSMUSP00000044417 | ENSMUSP00000035177 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family. | 0.992 |
Mrpl12 | Mrpl4 | ENSMUSP00000044417 | ENSMUSP00000003386 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.990 |
Mrpl12 | Mrpl41 | ENSMUSP00000044417 | ENSMUSP00000043561 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins. | 0.936 |
Mrpl12 | Mrpl47 | ENSMUSP00000044417 | ENSMUSP00000048078 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family. | 0.964 |
Mrpl12 | Mrpl9 | ENSMUSP00000044417 | ENSMUSP00000029786 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 39S ribosomal protein L9, mitochondrial; Belongs to the bacterial ribosomal protein bL9 family. | 0.999 |
Mrpl12 | Mrps18a | ENSMUSP00000044417 | ENSMUSP00000024763 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 28S ribosomal protein S18a, mitochondrial; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily. | 0.831 |
Mrpl12 | Mrps26 | ENSMUSP00000044417 | ENSMUSP00000123324 | 39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family. | 28S ribosomal protein S26, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS26 family. | 0.881 |